콘텐츠로 건너뛰기
Merck
모든 사진(1)

주요 문서

PHR1655

Supelco

Carbidopa

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C10H14N2O4 · H2O
CAS Number:
Molecular Weight:
244.24
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to BP 60
traceable to Ph. Eur. C0460000
traceable to USP 1095506

API family

carbidopa

CofA

current certificate can be downloaded

포장

pkg of 1 g

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

O.C[C@@](Cc1ccc(O)c(O)c1)(NN)C(O)=O

InChI

1S/C10H14N2O4.H2O/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4,12-14H,5,11H2,1H3,(H,15,16);1H2/t10-;/m0./s1

InChI key

QTAOMKOIBXZKND-PPHPATTJSA-N

유전자 정보

human ... DDC(1644)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Carbidopa is a peripheral decarboxylase inhibitor which is often formulated with levodopa for the management of the symptoms of Parkinson′s disease. Its mode of action involves the reduction of systemic production of dopamine and minimization of undesirable effects such as nausea.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

Carbidopa may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAA5756 in the slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Chaotropic agents in liquid chromatographic method development for the simultaneous analysis of levodopa, carbidopa, entacapone and their impurities
Vemic A, et al.
Journal of Pharmaceutical and Biomedical Analysis, 77(1-2), 9-15 (2013)
Stability-indicating method for the determination of levodopa, levodopa-carbidopa and related impurities
Kafil JB and Dhingra BS
Journal of Chromatography A, 667(1-2), 175-181 (1994)
Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3, 4-dihydroxyphenyl acetic acid
Karimi M, et al.
Journal of Chromatography. B, Biomedical Applications, 836(1-2), 120-123 (2006)
Simultaneous estimation of levodopa and carbidopa by RP-HPLC using a fluorescence detector: its application to a pharmaceutical dosage form
Raut PP and Charde SY
Luminescence, 29(7), 762-771 (2014)
Vayu Maini Rekdal et al.
Science (New York, N.Y.), 364(6445) (2019-06-15)
The human gut microbiota metabolizes the Parkinson's disease medication Levodopa (l-dopa), potentially reducing drug availability and causing side effects. However, the organisms, genes, and enzymes responsible for this activity in patients and their susceptibility to inhibition by host-targeted drugs are

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.