17772

Retinol

≥95.0% (HPLC), ~2700 U/mg

• 동의어(들): Axerophthol, Vitamin A, Vitamin A alcohol, Vitamin A₁, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
• 실험식(Hill 표기법): C₂₀H₃₀O
• CAS Number: 68-26-8
• Molecular Weight: 286.45
• Beilstein: 403040
• EC Number: 200-683-7
• MDL number: MFCD00001552
• UNSPSC 코드: 12352205
• eCl@ss: 34058018
• PubChem Substance ID: 329751561
• NACRES: NA.79

속성

• 생물학적 소스: synthetic
• Quality Level: 100
• 분석: ≥95.0% (HPLC)
• 양식: (Powder or Crystal with Lumps)
• 특이 활성도: ~2700 U/mg
• 색상: yellow to dark yellow
• mp: 61-63 °C (lit.)
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
• InChI: 1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
• InChI key: FPIPGXGPPPQFEQ-OVSJKPMPSA-N

설명

일반 설명

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinol is biologically active in a wide range of processes.

Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (all in trans configuration) and an alcohol end group.

애플리케이션

Retinol has been used as a standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS) for the vitamins detection and quantification.

생화학적/생리학적 작용

Retinol and its derivatives exhibit anti-aging properties. Retinol is used for treating wrinkles and signs of aging. However, due to its photo instability and skin irritation potency, it is hardly used in cosmetic formulations. Retinol is also used as a therapeutic for dermatoses. Its deficiency leads to xerosis and follicular hyperkeratosis.

단위 정의

1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H317,H319,H360FD,H413
• 예방조치 성명서: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves