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Merck
모든 사진(4)

문서

A4737

Sigma-Aldrich

Bovine Serum Albumin

lyophilized powder, protease, essentially free, ≥98% (agarose gel electrophoresis)

동의어(들):

Albumin from bovine serum, Albumin bovine serum, BSA, Bovine albumin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202

생물학적 소스

bovine

분석

≥98% (agarose gel electrophoresis)

형태

lyophilized powder

분자량

~66 kDa

포장

poly bottle of

기원

New Zealand origin

기술

ligand binding assay: suitable

불순물

≤8.0% water (Karl Fischer)

pH

4.8-7.5

solubility

H2O: soluble 50 mg/mL

UniProt 수납 번호

외래 활성

protease, essentially free

저장 온도

2-8°C

유전자 정보

bovine ... ALB(280717)

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일반 설명

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

애플리케이션

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry.

생화학적/생리학적 작용

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.
Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.

제조 메모

Purified by chromatography
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.
Sourced and manufactured in New Zealand

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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International journal of nanomedicine, 8, 1207-1222 (2013-04-10)
The livertaxis of glycyrrhizic acid-conjugated bovine serum albumin (GL-BSA) has been reported in the literature. Now, in this paper, we describe a novel type of drug-targeted delivery system containing 10-hydroxycamptothecin (HCPT) with liver tumor targeting. First, GL was coupled to
Karolina A Majorek et al.
Molecular immunology, 52(3-4), 174-182 (2012-06-09)
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