추천 제품
일반 설명
Curdlan is an insoluble natural polymer with linear structure mainly produced by Alcaligenes faecalis. It is a dietary fiber with gelatin properties.
애플리케이션
Curdlan from Alcaligenes faecalis has been used:
- for the stimulation of carp macrophages for regulation of differentially expressed genes
- to stimulate human intestinal epithelial cells for cytokine secretion
- to study its effect on transcriptional responses of inflammation/respiratory burst-associated genes in mouse alveolar macrophages by customized reverse transcription (RT)-PCR based arrays
- as a substrate in β-1,3–1,4-Glucanase activity assay
생화학적/생리학적 작용
Curdlan is a (1,3)-β-glucan. It is a pathogen-associated molecular-pattern (PAMP) recognized by the receptor dectin-1. Activation of dectin-1, together with TLR2/TLR6, promotes signaling resulting in the production of pro-inflammatory cytokines, thus inducing inflammation.
Curdlan is used as a food additive in the food industry. It improves the elasticity and reduces the embrittling tendency of hydroxyapatite/chitosan scaffold, which aids in bone regeneration.
제조 메모
For gelation at 70 °C, the concentration of the sodium hydroxide should be 0.01 M.
This product is tested for solubility in 0.1N sodium hydroxide at a concentration of 9.8 - 10.2 mg/mL. Heating and/or sonication are typically required for solubilization. This product is not sterile. For use in cell culture, stock solutions should be filter sterilized prior to use.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Nicola Jackson et al.
European journal of immunology, 44(4), 962-969 (2014-01-25)
Type B T cells recognize peptide-MHC class II (pMHCII) isoforms that are structurally distinct from those recognized by conventional type A T cells. These alternative type B conformers result from peptide loading in the absence of HLA-DM. Type A conformers
Characterisation of a novel Bacillus sp. SJ-10 I?-1,3-1,4-glucanase isolated from jeotgal, a traditional Korean fermented fish.
Kim, et al.
Bioprocess and Biosystems Engineering, 36, 721-727 (2013)
K N Masihi et al.
International journal of immunopharmacology, 19(9-10), 463-468 (1998-06-24)
The effects of glucan-based immunomodulators curdlan sulfate (CRDS) and lentinan on cytokine production stimulated by lipopolysaccharide (LPS) in bacillus Calmette-Guerin (BCG)-primed mice were investigated. Pretreatment with CRDS or lentinan before LPS administration induced a striking inhibition of up to 89%
Chunju An et al.
The Journal of biological chemistry, 284(29), 19716-19726 (2009-06-03)
Serine proteinases in insect plasma have been implicated in two types of immune responses; that is, activation of prophenoloxidase (proPO) and activation of cytokine-like proteins. We have identified more than 20 serine proteinases in hemolymph of the tobacco hornworm, Manduca
Microbial exopolisaccharides for biomedical applications
Journal of Material Science & Engineering, 165-219 (2019)
문서
당사는 다양한 항생제, 항바이러스제, 항진균제와 더불어 면역체계 신호전달 표적 식별 및 검증을 위한 작용제, 길항제, 조절제 및 기타 생체 활성 저분자를 제공합니다.
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.