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Merck
모든 사진(1)

주요 문서

F8190

Sigma-Aldrich

Fucoidan from Fucus vesiculosus

≥95%

동의어(들):

Fucoidin

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352201
NACRES:
NA.25

생물학적 소스

algae (Fucus Vesiculosus)

Quality Level

분석

≥95%

형태

powder

색상

light yellow

유용한 pH 범위

5.0-11.0

solubility

water: 10 mg/mL, clear, colorless to faintly yellow

저장 온도

room temp

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일반 설명

Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.

애플리케이션

Fucoidan from Fucus vesiculosus has been to:
  • study the application of heparin red in detecting fucoidan
  • study its bioactivity as an antimicrobial agent
  • study its effects on advanced glycation end-products

생화학적/생리학적 작용

Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation with subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.

기타 정보

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Bioactivity of Fucoidan as an Antimicrobial Agent in a New Functional Beverage
Poveda-Castillo et al.
Becker-Shaffer's Diagnosis and Therapy of the Glaucomas (2018)
Fanlu Wang et al.
Marine drugs, 19(4) (2021-04-04)
Fucoidans, sulfated polysaccharides extracted from brown algae, are marine products with the potential to modulate bone formation and vascularization processes. The bioactivity and safety of fucoidans are highly associated with their chemical structure, which may vary with algae species and
Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis
Shinichi H et al.
Scientific Reports, 8(1), 5901-5901 (2018)
Xinjia He et al.
Biological & pharmaceutical bulletin, 42(3), 442-447 (2019-03-05)
Fucoidan is an active component of seaweed, and could inhibit proliferation and induce apoptotic cell death in several tumor cells. However, the function of fucoidan in breast cancer is largely unknown. In the present study, we evaluated the anti-cancer potential
Hang T T Cao et al.
Marine drugs, 16(11) (2018-11-06)
Fucoidans from brown macroalgae have beneficial biomedical properties but their use as pharma products requires homogenous oligomeric products. In this study, the action of five recombinant microbial fucoidan degrading enzymes were evaluated on fucoidans from brown macroalgae: Sargassum mcclurei, Fucus

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