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Merck
모든 사진(3)

주요 문서

C9750

Sigma-Aldrich

β-Carotene

synthetic, ≥93% (UV), powder

동의어(들):

β,β-Carotene, Provitamin A

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About This Item

실험식(Hill 표기법):
C40H56
CAS Number:
Molecular Weight:
536.87
Beilstein:
1917416
EC Number:
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.79

생물학적 소스

synthetic

Quality Level

분석

≥93% (UV)

양식

powder

효능

~1,600,000 units vitamin A per g

색상

dark red to brown

mp

178-179 °C

solubility

hexane: 1.1 mg/mL
DMSO: 30 μg/mL

저장 온도

−20°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+

InChI key

OENHQHLEOONYIE-JLTXGRSLSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Carotenoids are an important class of naturally occurring pigments found in fruits and vegetables. Among the carotenoids, β-carotene has the greatest provitamin A potential and functions to reduce the risk of cancer, cardiovascular diseases and macular degeneration. Low water solubility and poor chemical stability attributes to low absorption of β-carotene from food. β-carotene along with digestible lipids enriches its bio accessibility. Emulsions or nano emulsions encapsulates effectively delivers lipophilic β-carotene and increases its bioavailability. β-carotene has anti-oxidant potential and reduces noise induced hearing loss and progression of macular degeneration.

애플리케이션

β-carotene has been used:
  • to generate nano emulsions to evaluate their bioavailability potential
  • as a standard, for β-carotene evaluation in blood and skin samples using high performance liquid chromatography (HPLC),
  • as a dietary supplement of vitamin-A in young rats by HPLC
  • as a dietary supplement in mice to reduce hearing loss and hair cell damage

생화학적/생리학적 작용

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

포장

Packaged in serum vials.

주의사항

Purchase minimum quantity required. Discard one month after opening.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

217.9 °F - closed cup

Flash Point (°C)

103.3 °C - closed cup

개인 보호 장비

Eyeshields, Gloves


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문서 라이브러리 방문

이미 열람한 고객

Colleen G Le Prell et al.
Free radical biology & medicine, 42(9), 1454-1463 (2007-03-31)
Free radical formation in the cochlea plays a key role in the development of noise-induced hearing loss (NIHL). The amount, distribution, and time course of free radical formation have been defined, including a clinically significant formation of both reactive oxygen
Qingqing Liu et al.
eLife, 5 (2016-05-25)
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Nutrient-enhanced diet reduces noise-induced damage to the inner ear and hearing loss
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Translational Research, 158(1), 38-53 (2011)
Effects of dietary brazilian palm oil (Mauritia flexuosa L.) on Cholesterol profile and Vitamin A and e status of rats
Aquino JD, et al.
Molecules (Basel), 20(5), 9054-9070 (2015)
Joamyr Victor Rossoni-Júnior et al.
Journal of clinical biochemistry and nutrition, 50(3), 177-183 (2012-05-11)
Annatto has been identified as carotenoids that have antioxidative effects. It is well known that one of the key elements in the development of diabetic complications is oxidative stress. The immune system is especially vulnerable to oxidative damage because many

문서

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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