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Merck
모든 사진(1)

문서

H6166

Sigma-Aldrich

Interferon α 2B human

HumanKine®, ≥95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture

동의어(들):

IFN α 2B, IFN Alfa 2b, INF α 2B, INF Alfa 2b, Interferon Alfa 2b

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About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.77

product name

Interferon α 2B human, IFN-α 2B, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

생물학적 소스

human

Quality Level

재조합

expressed in HEK 293 cells

분석

≥95% (SDS-PAGE)

형태

lyophilized powder

효능

≤0.12 ng/mL EC50

품질

endotoxin tested

분자량

dimer 16 kDa (glycosylated)

포장

poly bottle of 10 μg (in poly bottle)

제조업체/상표

HumanZyme

기술

cell culture | mammalian: suitable

불순물

≤1EU/mg

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

human ... IFNA2(3440)

일반 설명

The interferon α 2 (IFN-α2) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five α helices. IFN-α2B is found structurally stable at pH 7. The recombinant IFN-α is nonglycosylated compared to the natural human IFN-α.

생화학적/생리학적 작용

Interferon α 2B (IFN-α 2B) belongs to the type I interferon protein family. It is produced by many cell types in response to viral infection. IFN-α 2B has antiproliferative and antitumor activities, as well as induction of apoptosis and the inflammatory response. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides and activates cytotoxic T-cells.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

제조 메모

HumanKine IFN-α 2B is a glycosylated monomer expressed in HEK 293 cells with an apparent molecular mass of 16 kDa. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

분석 메모

The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV ( vesicular stomatitis virus).

법적 정보

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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