I6256
2-Iminothiolane hydrochloride
≥98% (TLC), powder
동의어(들):
2-Thiolanimine hydrochloride, 2IT, Dihydro-2(3H)-thiophenimine hydrochloride, Traut’s reagent
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모든 사진(4)
About This Item
실험식(Hill 표기법):
C4H7NS · HCl
CAS Number:
Molecular Weight:
137.63
Beilstein:
3620079
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.21
분석:
≥98% (TLC)
양식:
powder
solubility:
H2O: 100 mg/mL
추천 제품
일반 설명
2-Iminothiolane hydrochloride (2-IT.HCl), a protein modification reagent, is commonly employed to attach thiol groups to proteins and peptides. Raman spectroscopic analysis of hair keratin fibers modified with 2-IT.HCl showed the formation of new disulfide groups.
애플리케이션
2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be used to synthesize PLA-SH (polyethylene glycol-thiol) and PLA-PEG-SH (polyethylene glycol–polylactic acid-thiol).
Thiolating reagent for primary amines. Reacts at pH 7-10 by amidine bond to present free sulfhydryl. Useful in preparation of disulfide and/or thioether linked conjugates.
기타 정보
Note that the amidine linkage preserves original primary amine positive charge. Incorporates a five atom linker.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
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