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Merck
모든 사진(1)

주요 문서

M6532

Sigma-Aldrich

(+)-Muscarine chloride

~95% (TLC), powder

동의어(들):

(+)-(2S,4R,5S)-Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride, (+)-Tetrahydro-4β-hydroxy-N,N,N,5α-tetramethyl-2α-furanmethanaminium chloride

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About This Item

실험식(Hill 표기법):
C9H20ClNO2
CAS Number:
Molecular Weight:
209.71
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

분석

~95% (TLC)

Quality Level

양식

powder

색상

white

solubility

H2O: 50 mg/mL

SMILES string

[Cl-].C[C@@H]1O[C@@H](C[C@H]1O)C[N+](C)(C)C

InChI

1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1/t7-,8-,9+;/m0./s1

InChI key

WUFRNEJYZWHXLC-CTERPIQNSA-M

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Prototype muscarinic acetylcholine receptor agonist; active enantiomer.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

주의사항

Extremely hygroscopic

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Lourdes Mateos-Hernandéz et al.
Scientific reports, 10(1), 16054-16054 (2020-10-01)
Regulatory factors controlling tick salivary glands (SGs) are direct upstream neural signaling pathways arising from the tick's central nervous system. Here we investigated the cholinergic signaling pathway in the SG of two hard tick species. We reconstructed the organization of
I Slutsky et al.
The Journal of physiology, 514 ( Pt 3), 769-782 (1999-01-12)
1. Presynaptic effects of muscarine on neurotransmitter release were studied at the frog neuromuscular junction, using focal depolarization of the presynaptic terminal to different levels. 2. Muscarine (10 microM) had a dual effect on ACh release: concomitant inhibition and enhancement
A E Stewart et al.
Journal of neurophysiology, 81(1), 72-84 (1999-01-23)
We used the whole cell patch-clamp technique and single-cell reverse transcription-polymerase chain reaction (RT-PCR) to study the muscarinic receptor-mediated modulation of calcium channel currents in both acutely isolated and cultured pyramidal neurons from rat sensorimotor cortex. Single-cell RT-PCR profiling for
A G Karczmar
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 9(3), 181-199 (1993-11-01)
This year marks the seventieth anniversary of Otto Loewi's demonstration of chemical transmission generally and autonomic cholinergic transmission specifically and the fortieth anniversary of John Eccles's proof of the existence of central cholinergic transmission. Following these epochal findings, the subsequent
F J Evans
Journal of ethnopharmacology, 32(1-3), 91-101 (1991-04-01)
One traditional aspect of natural products in medical research has been their use in the identification and investigation of the physiological/pathological role of receptors and enzymes as possible targets for drug design programmes. Classical examples of this function of natural

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