추천 제품
사용
sufficient for 100 tests (Ultraviolet)
검출 방법
colorimetric
관련 질환(들)
cardiovascular diseases; genitourinary disorders; aging/geriatric diseases; orthopedic diseases
배송 상태
dry ice
저장 온도
−20°C
유전자 정보
human ... CKB(1152) , CKM(1158)
mouse ... CKB(12709) , CKM(12715)
rat ... CKB(24264) , CKM(24265)
일반 설명
Creatine Kinase (CK), also known as phosphocreatine kinase, is an enzyme that catalyzes the transfer of one phosphate group from ATP to creatine generating phosphocreatine, an important energy reservoir in muscle and brain tissue. CK is a dimeric protein made up of B (brain) and M (muscle) subunits. Three isoenzymes, CK-MM, CK-MB, and CK-BB, have been observed. CK levels are elevated in various pathological conditions including myocardial infarction, rhabdomyolysis, muscular dystrophy, and renal failure.
특징 및 장점
Compatible with high-throughput handling systems.
적합성
Suitable for the detection of Creatine Kinase activity in a variety of samples such as serum and plasma. This kit can be used to study the effects of various compounds on Creatine Kinase activity.
원리
Creatine Kinase activity is determined by a coupled enzyme reaction resulting in the production of NADPH, measured at 340 nm, proportionate to the CK activity present in the sample. In this reaction, phosphocreatine and ADP are converted to creatine and ATP. The generated ATP is used by hexokinase to phosphorylate glucose resulting in glucose-6-phosphate, which is oxidized by NADP in the presence of glucose-6-phosphate dehydrogenase to produce NADPH and 6-phospho-D-gluconate. One unit of CK is the amount of enzyme that will transfer 1.0 μmole of phosphate from phosphocreatine to ADP per minute at pH 6.0. This kit has a linear range of 30–1,800 units/L CK activity.
관련 제품
제품 번호
설명
가격
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Resp. Sens. 1
Storage Class Code
12 - Non Combustible Liquids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Marcus Waskiw-Ford et al.
Nutrients, 12(4) (2020-04-16)
Leucine-enriched essential amino acids (LEAAs) acutely enhance post-exercise myofibrillar protein synthesis (MyoPS), which has been suggested to be important for muscle repair and recovery. However, the ability of LEAAs to concurrently enhance MyoPS and muscle damage recovery in free-living humans
Gary R Hunter et al.
Medicine and science in sports and exercise, 49(12), 2414-2421 (2017-07-25)
Resting energy expenditure (REE) increases after an intense exercise; however, little is known concerning mechanisms. The purpose of this study was to determine effects of a single bout of moderate-intensity continuous (MIC) aerobic exercise, or high-intensity interval (HII) exercise on
P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy
Sinadinos A
PLoS Medicine null
Crystal structure of rabbit muscle creatine kinase.
Rao JK, et al.
Febs Letters, 133-7 null
Mon-Tzu Li et al.
Tissue engineering. Part A, 23(17-18), 989-1000 (2017-04-05)
High velocity impact injuries can often result in loss of large skeletal muscle mass, creating defects devoid of matrix, cells, and vasculature. Functional regeneration within these regions of large volumetric muscle loss (VML) continues to be a significant clinical challenge.
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