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Merck
모든 사진(1)

주요 문서

P6149

Sigma-Aldrich

Progesterone

γ-irradiated, BioXtra, suitable for cell culture

동의어(들):

4-Pregnene-3,20-dione

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About This Item

실험식(Hill 표기법):
C21H30O2
CAS Number:
Molecular Weight:
314.46
Beilstein:
1915950
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.77
생물학적 소스:
synthetic (organic)
양식:
powder
분석:
≥99%

생물학적 소스

synthetic (organic)

Quality Level

설명

synthesized from materials derived from plant source

무균

γ-irradiated

제품 라인

BioXtra

분석

≥99%

양식

powder

효능

0.1-20 ng/mL

기술

cell culture | mammalian: suitable

mp

128-132 °C (lit.)

solubility

chloroform: 50 mg/mL, clear, colorless to light yellow

배송 상태

ambient

저장 온도

room temp

SMILES string

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Use in cell culture applications to study sterol regulation of cell signaling and gene expression.

생화학적/생리학적 작용

Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation.
Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

기타 정보

Steroid hormone produced by the corpus luteum.

물리적 형태

powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw

재구성

To prepare 20 μg/ml stock solution, add 1 ml absolute ethanol, gently swirl to dissolve, add 49 ml sterile medium.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Nina Lisofsky et al.
NeuroImage, 118, 154-162 (2015-06-10)
Hippocampal volume has been shown to be sensitive to variations in estrogen and progesterone levels across rodents' estrous cycle. However, little is known about the covariation of hormone levels and brain structure in the course of the human menstrual cycle.
Rudolf Kaaks et al.
International journal of cancer, 134(8), 1947-1957 (2013-10-25)
Results from prospective studies on premenopausal serum hormone levels in relation to breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a case-control study nested within the prospective European Prospective Investigation into Cancer and Nutrition (EPIC)
Rudolf Kaaks et al.
Journal of the National Cancer Institute, 97(10), 755-765 (2005-05-19)
Contrasting etiologic hypotheses about the role of endogenous sex steroids in breast cancer development among premenopausal women implicate ovarian androgen excess and progesterone deficiency, estrogen excess, estrogen and progesterone excess, and both an excess or lack of adrenal androgens (dehydroepiandrosterone
Danijela Konforte et al.
Clinical chemistry, 59(8), 1215-1227 (2013-05-03)
Pediatric endocrinopathies are commonly diagnosed and monitored by measuring hormones of the hypothalamic-pituitary-gonadal axis. Because growth and development can markedly influence normal circulating concentrations of fertility hormones, accurate reference intervals established on the basis of a healthy, nonhospitalized pediatric population
Cathrin Brisken
Nature reviews. Cancer, 13(6), 385-396 (2013-05-25)
Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxifen, and aromatase

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