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Merck
모든 사진(4)

주요 문서

S5545

Sigma-Aldrich

Anti-Serotonin antibody produced in rabbit

whole antiserum

동의어(들):

Anti-Serotonin, Rabbit Anti-Serotonin, Serotonin Detection Antibody

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

whole antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

포함

15 mM sodium azide

종 반응성

rat, human

포장

antibody small pack of 25 μL

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:8,000 using sections of normal human appendix or serotonin-containing carcinoid tumors
immunohistochemistry (frozen sections): 1:5,000 using perfusion-fixed (4% paraformaldehyde), frozen sections of rat brain.

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... HTR1A(3350)

일반 설명

Serotonin/5-HT (5-hydroxytryptamine) is a neurotransmitters present in the brain. Anti-Serotonin specifically stains enterochromaffin cells in formalin-fixed, paraffin-embedded sections of normal human appendix and serotonin-containing carcinoid tumors. In the central nervous system (CNS), the antiserum reacts with serotonin-containing fibers in perfusion-fixed, free-floating sections of rat brain.

특이성

The antibody reacts with serotonin-containing fibers in paraformaldehyde perfusion-fixed, frozen sections of rat brain. The product specifically stains enterochromaffin cells in formalin-fixed, paraffin embedded sections of normal human appendix and serotonin-containing carcinoid tumors.

면역원

Serotonin creatinine sulfate complex conjugated with formaldehyde to BSA.

애플리케이션

Anti-Serotonin antibody has been used in immunocytochemistry.

생화학적/생리학적 작용

Serotonin/5-HT, the midbrain raphe system controls mood, emotion, cognition and motor functions, circadian and neuroendocrine rhythms, like food intake, sleep and reproductive activity. It participates in natural reward-related physiology and behaviour, from feeding to sexual activity.

물리적 형태

Supplied as a liquid containing 15 mM sodium azide as preservative.

저장 및 안정성

For continuous use, store at 2-8 °C for a maximum of one month. For extended storage freeze in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Roles for serotonin in neuroembryogenesis.
Bernard H, et al.
Serotonin, 477-506 (1981)
Martin Fritsch et al.
Frontiers in zoology, 10(1), 35-35 (2013-06-20)
One of the most interesting riddles within crustaceans is the origin of Cladocera (water fleas). Cladocerans are morphologically diverse and in terms of size and body segmentation differ considerably from other branchiopod taxa (Anostraca, Notostraca, Laevicaudata, Spinicaudata and Cyclestherida). In
Allelic Variation of Human Serotonin Transporter Gene Expression
Armin H, et al.
Journal of Neurochemistry, 66(6), 2621-2624 (1996)
Characterization of efferent projections of chemosensitive neurons in the caudal parapyramidal area of the rat brain
Ribas-Salgueiro JL, et al.
Brain Research Bulletin, 66(3), 235-248 (2005)
A review of central 5-HT receptors and their function
Barnes NM, et al.
Neuropharmacology, 38(8), 1083-1152 (1999)

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