S9549

Superoxide dismutase–polyethylene glycol from bovine erythrocytes

lyophilized powder, ≥1,350 units/mg protein

• 동의어(들): PEG-SOD
• MDL number: MFCD00678115
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 형태: lyophilized powder
• Quality Level: 400
• 특이 활성도: ≥1,350 units/mg protein
• 분자량: 5000 Da
• 구성: Protein, ≥20% biuret
• 라벨링 범위: ≥10 mol PEG per mol protein
• 저장 온도: −20°C

설명

일반 설명

Superoxide dismutase from bovine erythrocytes is a copper and zinc superoxide dismutase. Copper and zinc ions are coordinated by active site histidine residues. It has β-barrel structure.

애플리케이션

Superoxide dismutase-polyethylene glycol from bovine erythrocytes has been used:

• in the incubation of lung slices for measurement of dihydroethidium (DHE) fluorescence in cultured bovine pulmonary artery endothelial cells
• as supplement in T cell culture to investigate its effect on cytokine production
• in the preincubation of the carotid artery sections prior to DHE treatment

생화학적/생리학적 작용

Superoxide dismutase-polyethylene glycol (SOD-PEG) is effective than SOD in scavenging free radicals in injuries. It reduces oxidative damage in ovarian follicles cell culture and during ovarian tissue transplantation. SOD-PEG is also effective in scavenging superoxide in mitochondrial abnormalities.

포장

Package size based on protein content

기타 정보

Superoxide dismutase from bovine erythrocytes coupled to methoxy-polyethylene glycol, M.W. 5,000, through secondary amine linkage.

물리적 형태

Lyophilized powder containing PEG plus 5% citrate buffer salts

제조 메모

Enzyme derived

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H334
• 예방조치 성명서: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)