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Merck
모든 사진(2)

주요 문서

810253P

Avanti

dehydroergosterol (DHE)

ergosta-5,7,9(11),22-tetraen-3β-ol, powder

동의어(들):

DHE

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About This Item

실험식(Hill 표기법):
C28H42O
CAS Number:
Molecular Weight:
394.63
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 mg (with stopper and crimp cap (810253P-1mg))

제조업체/상표

Avanti Research - A Croda Brand 810253P

배송 상태

dry ice

저장 온도

−70°C

SMILES string

O[C@H]1CC[C@]2(C(=CC=C3[C@H]4[C@@]([C@H](CC4)[C@H](C)\C=C\[C@@H](C(C)C)C)(CC=C32)C)C1)C

InChI

1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1

InChI key

QSVJYFLQYMVBDR-CMNOFMQQSA-N

일반 설명

Dehydroergosterol (DHE) is a fluorescent sterol that possesses similar biophysical properties as cholesterol. It is found in yeast cells and other fungi.

애플리케이션

Dehydroergosterol (DHE) is suitable for the transfer of DHE from a population of donor (LD) to acceptor (LA) liposomes.

생화학적/생리학적 작용

Dehydroergosterol (DHE) is used for the visualization of intracellular traffic and intracellular transport kinetics.

포장

2 mL Amber Serum Vial with Stopper and Crimp Cap (810253P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Mohsen Pourmousa et al.
The journal of physical chemistry. B, 118(26), 7345-7357 (2014-06-04)
Although dehydroergosterol (DHE) is one of the most commonly used cholesterol (CHOL) reporters, it has remained unclear why it performs well compared with most other CHOL analogues and what its possible limitations are. We present a comprehensive study of the
Reynold Homan et al.
Analytical biochemistry, 441(1), 80-86 (2013-07-16)
We describe a simple but sensitive fluorescence method to accurately detect the esterification activity of lecithin:cholesterol acyltransferase (LCAT). The new assay protocol employs a convenient mix, incubate, and measure scheme. This is possible by using the fluorescent sterol dehydroergosterol (DHE)
Molecular basis for sterol transport by StART-like lipid transfer domains
Horenkamp FA, et al.
The Embo Journal, 37(6) (2018)
Olav Garvik et al.
Chemistry and physics of lipids, 159(2), 114-118 (2009-05-30)
The fluorescent sterol dehydroergosterol (DHE) is often used as a marker for cholesterol in cellular studies. We show by vesicle fluctuation analysis that DHE has a lower ability than cholesterol to stiffen lipid bilayers suggesting less efficient packing with phospholipid
Daniel Wüstner et al.
Microscopy research and technique, 74(1), 92-108 (2010-12-25)
Dehydroergosterol (DHE) is an intrinsically fluorescent sterol with absorption/emission in the ultraviolet (UV) region and biophysical properties similar to those of cholesterol. We compared the potential of UV-sensitive low-light-level wide-field (UV-WF) imaging with that of multiphoton (MP) excitation microscopy to

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