SRP6509

Chymotrypsin from human pancreas

≥95% (SDS-PAGE)

• 동의어(들): CLCR, CTRC, CTRC_HUMAN, Caldecrin, Chymotrypsin C, Chymotrypsin-C, ELA 4, Elastase 4, Elastase IV, Serum calcium decreasing factor
• EC Number: 232-671-2
• UNSPSC 코드: 12352204
• NACRES: NA.78

속성

• 생물학적 소스: human
• 분석: ≥95% (SDS-PAGE)
• 형태: lyophilized
• 분자량: 25 kDa
• 포장: pkg of 100 μg
• UniProt 수납 번호: Q99895
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... CTRC(11330)

설명

일반 설명

Chymotrypsin from human pancreas is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. It is secreted by the pancreas as inactive chymotrypsinogen C. Molecular weight of this enzyme is found to be 25kDa. The pI is 8.75.

생화학적/생리학적 작용

Chymotrypsin from human pancreas selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan and leucine. Loss-of-function mutations in this gene have been associated with increased risk of chronic pancreatitis. It has high activity toward leucyl peptide bonds. The enzyme acts as a co-activator of procarboxypeptidases A1 and A2.

물리적 형태

Lyophilized as a salt-free solid.

안전성 정보

• 픽토그램: GHS08,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H334,H335,H400
• 예방조치 성명서: P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1