569253-U

Discovery^® HS C18 (3 µm) HPLC Columns

L × I.D. 5 cm × 2.1 mm, HPLC Column

• 동의어(들): Discovery RP18 HPLC Column
• UNSPSC 코드: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

속성

• 제품명: Discovery^® HS C18 HPLC Column, 3 μm particle size, L × I.D. 5 cm × 2.1 mm
• material: stainless steel column
• Quality Level: 100
• Agency: suitable for USP L1
• 제품 라인: Discovery^®
• 특징: endcapped
• 제조업체/상표: Discovery^®
• 포장: 1 ea of
• 라벨링 범위: 20% Carbon loading
• 파라미터: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• 기술: HPLC: suitable; LC/MS: suitable
• 길이 × I.D.: 5 cm × 2.1 mm
• 표면적: 300 m²/g
• 표면 범위: 3.2 μmol/m²
• 불순물: <10 ppm metals
• Matrix: silica gel, high purity, spherical particle platform; fully porous particle
• 기질 활성군: C18 (octadecyl) phase
• 입자 크기: 3 μm
• 공극 크기: 120 Å
• 작동 pH 범위: 2-8
• 응용 분야: food and beverages
• 분리 기술: reversed phase

설명

일반 설명

Discovery^® HS C18 HPLC column (L × I.D. 5 cm × 2.1 mm) is commonly found to be stable under acidic and basic conditions.

애플리케이션

• Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery^® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).


• A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery^® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).


• Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery^® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).

특징 및 장점

• Stable, low bleed for LC-MS applications
• Scalable from analytical to preparatory
• Highly stable to ensure excellent run-to-run and lot-to-lot reproducibility
• Higher hydrophobicity for better resolution of difficult analytes

   

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany