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Merck
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문서

1066009

USP

Betamethasone

United States Pharmacopeia (USP) Reference Standard

동의어(들):

9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone

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About This Item

실험식(Hill 표기법):
C22H29FO5
CAS Number:
Molecular Weight:
392.46
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

생물학적 소스

synthetic

Grade

pharmaceutical primary standard

Agency

USP

vapor pressure

<0.0000001 kPa ( 25 °C)

API family

betamethasone

포장

pkg of 200 mg

제조업체/상표

USP

색상

white to off-white

mp

235-237 °C (lit.)
447.8-473 °F (231—245°C; decomposes)

solubility

acetone: sparingly soluble
chloroform: very slightly soluble
ethanol: sparingly soluble
ether: very slightly soluble
methanol: sparingly soluble
water: insoluble

density

0.305 g/cm3 at 25 °C (77°F)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChI key

UREBDLICKHMUKA-DVTGEIKXSA-N

유전자 정보

human ... NR3C1(2908)

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일반 설명

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Betamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Betamethasone Acetate
  • Betamethasone Oral Solution
  • Betamethasone Valerate Cream
  • Betamethasone Valerate Lotion
  • Betamethasone Valerate Ointment
  • Dexamethasone

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

관련 제품

제품 번호
설명
가격

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Repr. 1B - STOT RE 2

표적 기관

Liver,Kidney,Endocrine system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

이미 열람한 고객

Betamethasone
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(1), 541-541 (2020)
Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC
Santos-Montes A, et al.
Chromatographia, 39(9-10), 539-542 (1994)
Extraction-spectrophotometric method for the determination of betamethasone in pure form and in pharmaceutical formulations
Amin AS and Issa YM
Analytical Letters, 30(1), 69-78 (1997)
Analysis of betamethasone and its organic esters in pharmaceutical products
Graham RE, et al.
Journal of Pharmaceutical Sciences, 67(3), 360-363 (1978)
Development and validation of a stability-indicating RP-HPLC method for assay of betamethasone and estimation of its related compounds
Fu Q, et al.
Journal of Pharmaceutical and Biomedical Analysis, 51(3), 617-625 (2010)

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