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Merck
모든 사진(1)

주요 문서

모든 문서 보기

1356756

USP

Lamotrigine

United States Pharmacopeia (USP) Reference Standard

동의어(들):

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, GI 267119X

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C9H7Cl2N5
CAS Number:
84057-84-1
Molecular Weight:
256.09
MDL number:
MFCD00865333
UNSPSC 코드:
41116107
PubChem Substance ID:
329750224
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

lamotrigine

제조업체/상표

USP

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

Nc1nnc(c(N)n1)-c2cccc(Cl)c2Cl

InChI

1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)

InChI key

PYZRQGJRPPTADH-UHFFFAOYSA-N

유전자 정보

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

관련 카테고리

생화학적/생리학적 작용

Anticonvulsant.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

USP issued SDS can be found here.
Sales restrictions may apply.

관련 제품

제품 번호
설명
가격

픽토그램

Skull and crossbones
GHS06

신호어

Danger

유해 및 위험 성명서

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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문서 라이브러리 방문

Effect of Permeation enhancers on diffusion of lamotrigine drug through cellophane membrane.
Rao, Vinay, et al.
American Journal of Advanced Drug Delivery, 1.4, 606-610 (2013)
Allyson K Friedman et al.
Science (New York, N.Y.), 344(6181), 313-319 (2014-04-20)
Typical therapies try to reverse pathogenic mechanisms. Here, we describe treatment effects achieved by enhancing depression-causing mechanisms in ventral tegmental area (VTA) dopamine (DA) neurons. In a social defeat stress model of depression, depressed (susceptible) mice display hyperactivity of VTA
Zhi-fei Wang et al.
Acta pharmacologica Sinica, 32(12), 1433-1445 (2011-11-08)
The mood stabilizers lithium, valproate and lamotrigine are traditionally used to treat bipolar disorder. However, accumulating evidence suggests that these drugs have broad neuroprotective properties and may therefore be promising therapeutic agents for the treatment of neurodegenerative diseases, including stroke.
Philip J Wiffen et al.
The Cochrane database of systematic reviews, 12(12), CD006044-CD006044 (2013-12-04)
This is an update of the original Cochrane review entitled Lamotrigine for acute and chronic pain published in Issue 2, 2007, and updated in Issue 2, 2011. Some antiepileptic medicines have a place in the treatment of neuropathic pain (pain
Jacqueline A French et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 9(1), 176-184 (2011-12-06)
The efficacy and safety of lamotrigine extended-release tablets (LTG XR) as monotherapy for partial seizures were evaluated using the conversion-to-monotherapy design, and historical data as the control. This methodology was recently approved by the United States Food and Drug Administration
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