PHR1392
Lamotrigine
Pharmaceutical Secondary Standard; Certified Reference Material
동의어(들):
Lamotrigine, 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, GI 267119X
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C9H7Cl2N5
CAS Number:
Molecular Weight:
256.09
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to Ph. Eur. Y0001030
traceable to USP 1356756
API family
lamotrigine
CofA
current certificate can be downloaded
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-30°C
SMILES string
Nc1nnc(c(N)n1)-c2cccc(Cl)c2Cl
InChI
1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
InChI key
PYZRQGJRPPTADH-UHFFFAOYSA-N
유전자 정보
human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Lamotrigine is an anticonvulsant drug, which is widely used in the treatment of epilepsy and bipolar disorders. It is also used in combination with other antiepileptics to treat refractory partial seizures, generalized tonic-clonic seizures and generalized toxic-chronic seizures.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
애플리케이션
Labetalol Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
생화학적/생리학적 작용
Anticonvulsant.
분석 메모
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
기타 정보
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
각주
To see an example of a Certificate of Analysis for this material enter LRAC3640 in the slot below. This is an example certificate only and may not be the lot that you receive.
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
관련 제품
제품 번호
설명
가격
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Sensitive spectrophotometric determination of lamotrigine in bulk drug and pharmaceutical formulations using bromocresol green
Rajendraprasad N, et al.
Ecletica Quimica , 35(1), 55-66 (2010)
Spectrophotometric determination of lamotrigine in pharmaceutical preparations and urine by charge-transfer complexation
Alizadeh N, et al.
Pharmazie, 63(11), 791-795 (2008)
Allyson K Friedman et al.
Science (New York, N.Y.), 344(6181), 313-319 (2014-04-20)
Typical therapies try to reverse pathogenic mechanisms. Here, we describe treatment effects achieved by enhancing depression-causing mechanisms in ventral tegmental area (VTA) dopamine (DA) neurons. In a social defeat stress model of depression, depressed (susceptible) mice display hyperactivity of VTA
Philip J Wiffen et al.
The Cochrane database of systematic reviews, 12(12), CD006044-CD006044 (2013-12-04)
This is an update of the original Cochrane review entitled Lamotrigine for acute and chronic pain published in Issue 2, 2007, and updated in Issue 2, 2011. Some antiepileptic medicines have a place in the treatment of neuropathic pain (pain
Zhi-fei Wang et al.
Acta pharmacologica Sinica, 32(12), 1433-1445 (2011-11-08)
The mood stabilizers lithium, valproate and lamotrigine are traditionally used to treat bipolar disorder. However, accumulating evidence suggests that these drugs have broad neuroprotective properties and may therefore be promising therapeutic agents for the treatment of neurodegenerative diseases, including stroke.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.