MilliporeSigma

IL4

interleukin 4

Synonyms:
BCGF-1, BCGF1, BSF-1, BSF1, IL-4
Species:
UniProtKB ID:
Gene ID:
  • Human(3565) Summary: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(16189) interleukin 4
  • Rat(287287) interleukin 4
  • Zebrafish(100188894) interleukin 4
  • chicken(416330) interleukin 4
  • dog(403785) interleukin 4
  • domestic cat(751514) interleukin 4
  • Horse(100034225) interleukin 4
  • cow(280824) interleukin 4
  • Goat(100860814) interleukin 4
  • sheep(101122781) interleukin 4
  • sheep(443327) interleukin 4
  • Domestic Rabbit(100302454) interleukin 4
  • naked mole-rat(101706414) interleukin 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Porcine IL4 / Interleukin-4 ELISA Kit, ,
Species
Feline IL4 / Interleukin-4 ELISA Kit, ,
Species
domestic cat
Equine IL4 / Interleukin-4 ELISA Kit, ,
Species
horse
Mouse IL-4 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Mouse IL-4 ELISA Kit, for cell and tissue lysates,
Species
mouse

Small Molecule - Antagonist

Product Number
Description
Species
Myricetin, ≥96.0% (HPLC),
Species
rat, mouse, human
Myricetin, ≥96.0%, crystalline,
Species
rat, mouse, human
Luteolin, ≥98% (TLC), powder,
Species
rat, human, mouse
Terfenadine, ,
Species
mouse, rat, human
Betamethasone, ≥98%,
Species
mouse, rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL-4 Antibody, clone 2D7.14.8, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-Hepatocyte Growth Factor antibody produced in mouse, clone 24516, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-Interleukin-4 antibody produced in mouse, clone 3007, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
immunohistochemistry
neutralization

western blot
Anti-IL4 Antibody, clone 9E10T0, Rabbit Monoclonal, ,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-IL-4 (mouse), APC, clone 11B11 Antibody, clone 11B11, from rat, Allophycocyanin conjugate,
Species Reactivity
mouse
Application
flow cytometry

Proteins

Product Number
Description
Species
IL-4 human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
IL-4 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human
Interleukin-4 from mouse, IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
mouse
IL-4 from mouse, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
Interleukin-4 human, IL-4, potency:, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human