Skip to Content
MilliporeSigma
All Photos(1)

Documents

170216

Sigma-Aldrich

Methylglyoxal 1,1-dimethyl acetal

≥97%

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
1,1-Dimethoxyacetone, Pyruvaldehyde-1-dimethyl acetal, Pyruvic aldehyde dimethyl acetal
Linear Formula:
CH3COCH(OCH3)2
CAS Number:
6342-56-9
Molecular Weight:
118.13
Beilstein/REAXYS Number:
1560557
EC Number:
228-735-4
MDL number:
MFCD00008758
UNSPSC Code:
12352100
PubChem Substance ID:
24850288
NACRES:
NA.22

Quality Level

200

assay

≥97%

form

liquid

refractive index

n20/D 1.398 (lit.)

bp

143-147 °C (lit.)

density

0.976 g/mL at 25 °C (lit.)

SMILES string

COC(OC)C(C)=O

InChI

1S/C5H10O3/c1-4(6)5(7-2)8-3/h5H,1-3H3

InChI key

ULVSHNOGEVXRDR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

application

Methylglyoxal 1,1-dimethyl acetal was used in the synthesis of methylglyoxal via hydrolysis in the presence of H2SO4. It was used to investigate the effects of methylglyoxal-mediated glycation on the structure, thermal stability and enzyme activity of yeast enolase in vivo.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

wgk_germany

WGK 1

flash_point_f

closed cup

flash_point_c

closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

DL-Lactaldehyde solution ~1 M in H2O

Sigma-Aldrich

49426

DL-Lactaldehyde solution

L-Lactaldehyde solution 1 M in H2O

Sigma-Aldrich

47014

L-Lactaldehyde solution

3,3-Dimethyloxetane 98%

Sigma-Aldrich

192309

3,3-Dimethyloxetane

Acetone-13C3 99 atom % 13C

Sigma-Aldrich

491667

Acetone-13C3

Glyoxal solution for molecular biology, BioReagent, ~40% in H2O (~8.8 M)

Sigma-Aldrich

50649

Glyoxal solution

Svetlana I Dorovskikh et al.
Biomedicines, 9(8) (2021-08-28)
This work is aimed at developing the modification of the surface of medical implants with film materials based on noble metals in order to improve their biological characteristics. Gas-phase transportation methods were proposed to obtain such materials. To determine the
Ricardo A Gomes et al.
The FEBS journal, 272(17), 4521-4531 (2005-09-01)
Methylglyoxal is the most important intracellular glycation agent, formed nonenzymatically from triose phosphates during glycolysis in eukaryotic cells. Methylglyoxal-derived advanced glycation end-products are involved in neurodegenerative disorders (Alzheimer's, Parkinson's and familial amyloidotic polyneurophathy) and in the clinical complications of diabetes.
Ajit Ghosh et al.
Scientific reports, 6, 18358-18358 (2016-01-07)
Glyoxalase pathway, comprising glyoxalase I (GLY I) and glyoxalase II (GLY II) enzymes, is the major pathway for detoxification of methylglyoxal (MG) into D-lactate involving reduced glutathione (GSH). However, in bacteria, glyoxalase III (GLY III) with DJ-1/PfpI domain(s) can do
Giulia Milordini et al.
Frontiers in molecular biosciences, 7, 104-104 (2020-06-26)
Epidemiological evidence shows an increased risk for developing Alzheimer's disease in people affected by diabetes, a pathology associated with increased hyperglycemia. A potential factor that could explain this link could be the role that sugars may play in both diseases
K Ispolnov et al.
Journal of applied microbiology, 104(4), 1092-1102 (2008-01-16)
The purpose of this study was to investigate the behaviour of Saccharomyces cerevisiae in response to extracellular methylglyoxal. Cell survival to methylglyoxal and the importance of phosphates was investigated. The role of methylglyoxal detoxification systems and methylglyoxal-derived protein glycation were
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service