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531154

Sigma-Aldrich

Poly(D,L-lactide-co-glycolide)

average Mw 5,000-15,000, lactide:glycolide (50:50)

Synonym(s):

PLGA

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About This Item

Linear Formula:
[C3H4O2]x[C2H2O2]y
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:

feed ratio

lactide:glycolide (50:50)

mol wt

average Mw 5,000-15,000

inherent viscosity

0.15-0.25 dL/g(lit.)

transition temp

Tg (DSC) 24 °C (onset)

SMILES string

OCC(O)=O.CC(O)C(O)=O

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Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Claus G Madsen et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 92, 1-7 (2015-02-11)
This study describes how protein release from polymer matrices correlate with simple measurements on the intrinsic viscosity of the polymer solutions used for casting the matrices and calculations of the solubility parameters of polymers and solvents used. Matrices of poly(dl-lactide-co-glycolide)

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