MilliporeSigma
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P2066

Sigma-Aldrich

Poly(D,L-lactide-co-glycolide)

lactide:glycolide 65:35, Mw 40,000-75,000

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Synonym(s):
Lactel® B6001-1, PLGA
Linear Formula:
[C3H4O2]x[C2H2O2]y
MDL number:
PubChem Substance ID:
NACRES:
NA.23

form

pellets

Quality Level

feed ratio

lactide:glycolide 65:35

mol wt

Mw 40,000-75,000

storage temp.

−20°C

SMILES string

OCC(O)=O.CC(O)C(O)=O

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This Item
802182P1941908843
storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

feed ratio

lactide:glycolide 65:35

feed ratio

lactide:glycolide (50:50)

feed ratio

lactide:glycolide (75:25)

feed ratio

lactide:glycolide 75:25

mol wt

Mw 40,000-75,000

mol wt

average Mw 100,000

mol wt

66,000-107,000

mol wt

PEG average Mn 1,500 (by NMR), PLGA average Mn 3,200 (by NMR), average Mn (1,600-1,500-1,600)

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Legal Information

Lactel is a registered trademark of Evonik Corp

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Eleftheria Babaliari et al.
International journal of molecular sciences, 19(7) (2018-07-18)
Cell responses depend on the stimuli received by the surrounding extracellular environment, which provides the cues required for adhesion, orientation, proliferation, and differentiation at the micro and the nano scales. In this study, discontinuous microcones on silicon (Si) and continuous
Patrick Vavken et al.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 29(1), 122-132 (2012-12-04)
The objective of this study was to assess the effect of absorbable or nonabsorbable sutures in bioenhanced anterior cruciate ligament (ACL) repair in a skeletally immature pig model on suture tunnel and growth plate healing and biomechanical outcomes. Sixteen female
Daniel R Getts et al.
Nature biotechnology, 30(12), 1217-1224 (2012-11-20)
Aberrant T-cell activation underlies many autoimmune disorders, yet most attempts to induce T-cell tolerance have failed. Building on previous strategies for tolerance induction that exploited natural mechanisms for clearing apoptotic debris, we show that antigen-decorated microparticles (500-nm diameter) induce long-term
Kyle E Broaders et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(14), 5497-5502 (2009-03-27)
Materials that combine facile synthesis, simple tuning of degradation rate, processability, and biocompatibility are in high demand for use in biomedical applications. We report on acetalated dextran, a biocompatible material that can be formed into microparticles with degradation rates that
Hannu Paajanen et al.
International journal of surgery (London, England), 11(1), 81-84 (2012-12-19)
Chronic pain may be a major long-term problem related to mesh material and operative trauma in inguinal hernioplasty. Lichtenstein hernioplasty was performed under local anaesthesia in 312 patients by the same surgeon and technique between 2003 and 2005. The patients

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