719919
amorphous
lactide:glycolide 75:25
Mw 4,000-15,000
<6 months
0.14-0.22 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)
Tg 42-46 °C
2-8°C
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
LCSKNASZPVZHEG-UHFFFAOYSA-N
1 of 4
This Item | 719927 | 719900 | 739979 |
---|---|---|---|
viscosity 0.14-0.22 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer) | viscosity 0.71-1.0 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer) | viscosity 0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer) | viscosity 1.3-1.7 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer) |
transition temp Tg 42-46 °C | transition temp Tg 49-55 °C | transition temp Tg 46-50 °C | transition temp - |
storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
feed ratio lactide:glycolide 75:25 | feed ratio lactide:glycolide 75:25 | feed ratio lactide:glycolide 50:50 | feed ratio lactide:glycolide 85:15 |
mol wt Mw 4,000-15,000 | mol wt Mw 76,000-115,000 | mol wt Mw 38,000-54,000 | mol wt Mw 190,000-240,000 |
11 - Combustible Solids
WGK 3
Not applicable
Not applicable
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Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).
Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.
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