MilliporeSigma

1.37003

SAFC

Citric acid monohydrate

crystalline, EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, ACS

Synonym(s):
2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
Linear Formula:
HOC(COOH)(CH2COOH)2 · H2O
CAS Number:
Molecular Weight:
210.14
Beilstein:
4018641
MDL number:
EC Index Number:
201-069-1

grade

ACS reagent

Quality Level

Agency

BP
JP
Ph. Eur.
USP

vapor pressure

<1 Pa ( 25 °C)

description

cryst. EMPROVE® EXPERT Ph Eur,BP,JP,USP,ACS

product line

EMPROVE® EXPERT

form

crystalline
solid

pH

1.85 (25 °C, 50 g/L in H2O)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

135-152 °C

transition temp

flash point 173.9 °C

solubility

880 g/L

density

1.54 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

15-25°C

SMILES string

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

InChI key

YASYEJJMZJALEJ-UHFFFAOYSA-N

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Citric acid monohydrate crystalline, EMPROVE&#174; EXPERT, Ph. Eur., BP, JP, USP, ACS

SAFC

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Citric acid monohydrate

Citric acid monohydrate powder, EMPROVE&#174; ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 330

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Citric acid monohydrate

Citric acid monohydrate crystalline, EMPROVE&#174; ESSENTIAL, Ph. Eur., BP, ChP, USP, FCC, E 330

SAFC

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Citric acid monohydrate

Citric acid monohydrate for analysis EMSURE&#174; ACS,ISO,Reag. Ph Eur

Supelco

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agency

BP, JP, Ph. Eur., USP

agency

BP, ChP, JP, Ph. Eur., USP

agency

BP, ChP, Ph. Eur., USP

agency

reag. ISO, reag. Ph. Eur.

vapor pressure

<1 Pa ( 25 °C)

vapor pressure

<1 Pa ( 25 °C)

vapor pressure

<1 Pa ( 25 °C)

vapor pressure

<1 Pa ( 25 °C)

form

crystalline, solid

form

fine powder

form

coarse powder, crystalline

form

solid

pH

1.85 (25 °C, 50 g/L in H2O)

pH

1.85 (25 °C, 50 g/L in H2O)

pH

1.85 (25 °C, 50 g/L in H2O)

pH

1.85 (25 °C, 50 g/L in H2O)

mp

135-152 °C

mp

135-152 °C

mp

135-152 °C

mp

135-152 °C

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Citric acid anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Citric acid anhydrous Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

345.0 °F - closed cup

Flash Point(C)

173.9 °C - closed cup


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