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Key Documents

8.08742

Sigma-Aldrich

N,N,N′,N′-Tetramethyl ethylenediamine

for synthesis

Synonym(s):

N,N,N′,N′-Tetramethyl ethylenediamine, TEMED, TMEDA, 1,2-Bis(dimethylamino)ethane

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About This Item

Linear Formula:
(CH3)2NCH2CH2N(CH3)2
CAS Number:
110-18-9
Molecular Weight:
116.20
MDL number:
MFCD00008335
UNSPSC Code:
12352116
EC Index Number:
203-744-6
NACRES:
NA.22

vapor pressure

21 hPa ( 20 °C)

Quality Level

200

assay

≥99.0% (GC)

form

liquid

autoignition temp.

145 °C

potency

5390 mg/kg LD50, skin (Rabbit)

expl. lim.

1-9 % (v/v)

pH

8.0-8.5 (20 °C, 0.1 g/L in H2O)

bp

121 °C/1013 hPa

mp

-55 °C

transition temp

flash point 19 °C

density

0.78 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C6H16N2/c1-7(2)5-6-8(3)4/h5-6H2,1-4H3

InChI key

KWYHDKDOAIKMQN-UHFFFAOYSA-N

Application


  • Surface Basicity and Hydrophilic Character of Coal Ash-Derived Zeolite NaP1 Modified by Fatty Acids: This study discusses the modification of Zeolite NaP1 with N,N,N′,N′-tetramethylethylenediamine to assess changes in surface basicity and hydrophilic character, relevant for environmental chemistry and materials science (AP Beltrão-Nunes, M Pires, R Roy, A Azzouz, 2024).

  • Horseradish peroxidase-catalyzed polyacrylamide gels: Explores the use of N,N,N′,N′-tetramethylethylenediamine in the polymerization of polyacrylamide gels, enhancing the understanding of gel-based biomolecular analysis systems (C Liao, T Li, F Chen, S Yan, L Zhu, H Tang, D Wang, 2024).

  • Photoinduced Alkylsulfonylation and Cyanoalkylsulfonylation of Morita–Baylis–Hillman Adducts: Demonstrates the role of N,N,N′,N′-tetramethylethylenediamine in photochemical synthesis, providing insights into organic synthesis mechanisms (ZJ Song, Y Bao, YJ Sun, S Yan, Y Zhang, 2024).

  • Probing coordination geometry and electronic nature of Cu center in mixed ligand copper complexes: This research utilizes N,N,N′,N′-tetramethylethylenediamine to study the coordination geometry and electronic properties of copper complexes, significant for inorganic chemistry and catalysis (M Bairagi, VK Hinge, N Yadav, SK Joshi, 2024).

  • Indirect Adhesion of Hydrogels via the Radical Polymerization: Investigates the use of N,N,N′,N′-tetramethylethylenediamine in creating an indirect adhesive system for hydrogels, relevant to material science and polymer chemistry (R Okada, S Tamesue, 2024).


Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.774 - 0.777
Water (K. F.): ≤ 0.50 %
Identity (IR): passes test

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

61.7 °F - closed cup

flash_point_c

16.5 °C - closed cup

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