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Human Leptin "Dual Range" ELISA

This Human Leptin "Dual Range" ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

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Synonym(s):
Leptin, Obesity factor
eCl@ss:
32161000
NACRES:
NA.32

Quality Level

species reactivity

human

assay range

accuracy: 94-114%
intra-assay cv: 1.4-4.9
(Sensitive Assay)

intra-assay cv: 2.6-4.6
linearity: 80-105%
linearity: 96-125%
(sensitive assay)

sensitivity: 0.125 ng/mL
(sensitive assay)

sensitivity: 0.125-20 ng/mL
sensitivity: 0.5 ng/mL
standard curve range: 0.5-100 ng/mL

technique(s)

ELISA: suitable

NCBI accession no.

UniProt accession no.

detection method

colorimetric
fluorometric

Gene Information

human ... LEP(3952)

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Human Leptin "Dual Range" ELISA This Human Leptin "Dual Range" ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

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species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

mouse

assay range

accuracy: 94-114%, intra-assay cv: 2.6-4.6, linearity: 96-125%
(sensitive assay), sensitivity: 0.125-20 ng/mL, standard curve range: 0.5-100 ng/mL, intra-assay cv: 1.4-4.9
(Sensitive Assay), sensitivity: 0.125 ng/mL
(sensitive assay), linearity: 80-105%, sensitivity: 0.5 ng/mL

assay range

accuracy: 92-102%, intra-assay cv: 1.0-7.4, linearity: 81-100%, sensitivity: 1.5 ng/mL, standard curve range: 1.5-100 ng/mL
(adiponection)

assay range

-

assay range

accuracy: 99-112%, linearity: 96-121%, sensitivity: 0.78 ng/mL, standard curve range: 0.78-50 ng/mL

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

detection method

colorimetric, fluorometric

detection method

colorimetric, fluorometric

detection method

colorimetric, fluorometric

detection method

colorimetric, fluorometric

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

General description

Leptin is a hormone that is secreted by the adipose tissue. It is also produced by the gastrointestinal tract and placenta. Leptin consists of a four-helix bundle. Leptin participates in regulating appetite, body weight, and energy expenditure. Excessive leptin is associated with cardiovascular complications like hypertension, coronary heart disease, and stroke. The LEP gene is mapped on the human chromosome at 7q32.1. Human Leptin "Dual Range" enzyme-linked immunosorbent assay (ELISA) kit is used for the non-radioactive quantification of human leptin in serum, plasma, and other biological media.

Application

Human Leptin "Dual Range" ELISA kit has been used in the analysis of leptin in:
  • blood samples
  • serum samples
  • plasma samples

pictograms

CorrosionExclamation mark

signalword

Warning

Hazard Classifications

Met. Corr. 1 - Skin Sens. 1

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3


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P Prolo et al.
The international journal of biochemistry & cell biology, 30(12), 1285-1290 (1999-01-30)
Leptin is an adipocyte hormone that signals nutritional status to the central nervous system (CNS) and peripheral organs. Leptin is also synthetized in the placenta and in gastrointestinal tract, although its role in these tissues is not yet clear. Circulating
A study on biomarkers, cytokines, and growth factors in children with burn injuries.
N M Abdel-Hafez,Y Saleh Hassan,T H El-Metwally
Annals of Burns and Fire Disasters null
Metabolic state alters economic decision making under risk in humans.
Symmonds, Mkael, et al.
Testing, 5, e11090-e11090 (2010)
Lydia Foucan et al.
The Journal of clinical endocrinology and metabolism, 103(2), 539-545 (2017-12-08)
The population of Guadeloupe Island exhibits a high prevalence of obesity. We aimed to investigate whether rare genetic mutations in genes involved in monogenic obesity (or diabetes) might be causal in this population of Afro-Caribbean ancestry. This was a secondary
Thamonwan Imerbtham et al.
Diabetes, metabolic syndrome and obesity : targets and therapy, 13, 925-933 (2020-04-11)
The purposes of this study were to use speckle tracking echocardiography to confirm the influence of obesity on cardiac functions and to assess their relationships with leptin and uric acid levels in obese adolescents. Eighty-one participants aged 16-19 years were

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