31493

Sodium salicylate

puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

• Synonym(s): 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate
• Linear Formula: HOC₆H₄COONa
• CAS Number: 54-21-7
• Molecular Weight: 160.10
• Beilstein/REAXYS Number: 3732792
• EC Number: 200-198-0
• MDL number: MFCD00002440
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648580
• NACRES: NA.21
• assay: 99.5-101.0% (calc. to the dried substance)

Properties

• agency: USP/NF; reag. Ph. Eur.
• Quality Level: 100
• grade: puriss. p.a.
• assay: 99.5-101.0% (calc. to the dried substance)
• impurities: acidic reac. impurities, complies; sulfite or thiosulfate, complies; ≤0.001% heavy metals (as Pb)
• loss: ≤0.3% loss on drying, 105 °C
• mp: >300 °C (lit.)
• anion traces: chloride (Cl^-): ≤20 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• cation traces: Fe: ≤10 mg/kg
• suitability: in accordance for appearance of solution

Description

General description

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.[1]

Application

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia.[2] It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from mixed micelles.[3]

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H319,H361d
• pcodes: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 208.9 °F - Pensky-Martens closed cup
• flash_point_c: 98.3 °C - Pensky-Martens closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves