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372978

Sigma-Aldrich

Chloroform

anhydrous, contains amylenes as stabilizer, ≥99%

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Synonym(s):
Methylidyne trichloride, Trichloromethane
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
Molecular Weight:
119.38
Beilstein/REAXYS Number:
1731042
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

anhydrous

Quality Level

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99%

form

liquid

contains

amylenes as stabilizer

packaging

Sure/Seal of 1, 6x1, 2 L
Pure-Pac® 2 of 20 L (USA only)

impurities

<0.001% water
0.005% water (100mL)

evapn. residue

<0.0003%

color

colorless

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.48 g/mL at 25 °C
1.492 g/mL at 25 °C (lit.)

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

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This Item
319988496189480150
vibrant-m

372978

Chloroform

-
vibrant-m

319988

Chloroform

Essential Grade
vibrant-m

496189

Chloroform

-
vibrant-m

480150

Chloroform

-
assay

≥99%

assay

≥99.8%

assay

≥99.8%

assay

≥99.8%

grade

anhydrous

grade

ACS reagent

grade

biotech. grade

grade

ACS reagent

density

1.48 g/mL at 25 °C, 1.492 g/mL at 25 °C (lit.)

density

1.48 g/mL at 25 °C, 1.492 g/mL at 25 °C (lit.)

density

1.48 g/mL at 25 °C, 1.492 g/mL at 25 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

bp

60.5-61.5 °C (lit.)

bp

60.5-61.5 °C (lit.)

bp

60.5-61.5 °C (lit.)

bp

60.5-61.5 °C (lit.)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

General description

Chloroform is an organic solvent that can beproduced by the chlorination of methane or lower-chlorinated methanes.

Application

Chloroform can be used as a solvent:
  • To synthesize diaryl ketones.
  • In the palladium-catalyzed cross-coupling reaction of aryl­boronic acids with acid chlorides under the phosphine-free condition to synthesize aryl ketones.
It can also be used as a phosgene precursor in Friedel-Crafts-type aminocarbonylation.(3)

Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany
Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

ppe

Eyeshields, Faceshields, Gloves


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