MilliporeSigma

1.02431

SAFC

Chloroform

EMPROVE® ESSENTIAL

Synonym(s):
TCM, Trichloromethane, Methane trichloride, Methyl trichloride, Methylidyne trichloride, Trichloromethane
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
Molecular Weight:
119.38
Beilstein:
1731042
MDL number:
EC Index Number:
200-663-8

vapor density

4.1 (vs air)

Quality Level

vapor pressure

160 mmHg ( 20 °C)

product line

EMPROVE® ESSENTIAL

Assay

99.0-99.4% (GC)

form

liquid

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

application(s)

liquid formulation
pharmaceutical

storage temp.

2-30°C

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

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This Item
1.070243199881.02432
Chloroform EMPROVE® ESSENTIAL

SAFC

1.02431

Chloroform

Chloroform for analysis EMPARTA® ACS

Supelco

1.07024

Chloroform

Chloroform contains ethanol as stabilizer, ACS reagent, ≥99.8%

Sigma-Aldrich

319988

Chloroform

Chloroform for gas chromatography ECD and FID SupraSolv®

Supelco

1.02432

Chloroform

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

assay

99.0-99.4% (GC)

assay

≥99.8% (according to ACS), 99.0-99.4% (GC)

assay

≥99.8%

assay

≥99.8% (GC)

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

API processing | polymorph screening: suitable

technique(s)

-

technique(s)

-

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Chloroform is used in pharmaceutical production processes and as an inactivation ingredient in vaccines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Certificates of Analysis (COA)

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25G
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