60018

Caffeic acid

matrix substance for MALDI-MS, ≥99.0% (HPLC)

• Synonym(s): 3,4-Dihydroxybenzeneacrylic acid, 3,4-Dihydroxycinnamic acid, 3-(3,4-Dihydroxyphenyl)-2-propenoic acid
• Linear Formula: (HO)₂C₆H₃CH=CHCO₂H
• CAS Number: 331-39-5
• Molecular Weight: 180.16
• Beilstein/REAXYS Number: 1954563
• EC Number: 206-361-2
• MDL number: MFCD00004392
• UNSPSC Code: 12000000
• PubChem Substance ID: 329758737
• NACRES: NA.21

Properties

• grade: matrix substance for MALDI-MS
• Quality Level: 100
• assay: ≥99.0% (HPLC)
• form: powder
• analyte chemical class(es): peptides, proteins
• technique(s): MALDI-MS: suitable
• color: slightly beige
• mp: 211-213 °C (dec.) (lit.)
• cation traces: Ba: ≤5 mg/kg; Ca: ≤20 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤20 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤20 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• suitability: in accordance for UV test
• SMILES string: OC(=O)\C=C\c1ccc(O)c(O)c1
• InChI: 1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+
• InChI key: QAIPRVGONGVQAS-DUXPYHPUSA-N

Description

General description

Caffeic acid is an antioxidant and the major hydroxycinnamic acid present in wine. It contains a catechol group with an α,β-unsaturated carboxylic acid chain with hepatoprotective properties.

Application

Caffeic acid may be used as an electrocatalysis mediator in voltammetric determination of cysteamine (CA) in an aqueous buffer solution.

Biochem/physiol Actions

A natural dietary phenolic compound found in plants that is an anti-oxidant. Inhibits the synthesis of leukotrienes that are involved in immunoregulation, inflammation and allergy. Inhibits Cu²⁺-induced LDL oxidation.

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H351
• pcodes: P280
• Hazard Classifications: Carc. 2
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges