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B1502

Sigma-Aldrich

Brain Extract from bovine brain

Type I, Folch Fraction I

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Synonym(s):
Brain Extract from Bovine
NACRES:
NA.25

biological source

bovine brain

Quality Level

type

Type I

form

powder

lipid type

phosphoglycerides

storage temp.

−20°C

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This Item
B3635P7693C4905
Brain Extract from bovine brain Type I, Folch Fraction I

B1502

Brain Extract from bovine brain

Sigma-Aldrich

B3635

Brain Extract from bovine brain

form

powder

form

powder

form

lyophilized powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

type

Type I

type

Type VII

type

Type I

type

-

lipid type

phosphoglycerides

lipid type

phosphoglycerides

lipid type

phosphoglycerides

lipid type

-

General description

Brain extract has lipids, especially polyunsaturated fatty acids (PUFAs) at high level. Extract from substantia niagra and the striatum has high amount of iron.

Application

Brain Extract from bovine brain has been used:
  • to prepare small unilamellar vesicles
  • in lipid binding assay
  • to aid the recovery of phosphoinositides and also to terminate the reaction in phosphatidylinositol 5-phosphate (PtdIns5P) and PtdIns4P assay
  • in liposome and protein self-aggregation assays

Biochem/physiol Actions

Brain lipids are involved in cellular signal transduction, membrane organization, trafficking protein modification, interactions and energy storage.

Packaging

Sealed ampule.

Components

Contains phosphatidylinositol phosphatidylserine,other brain lipids.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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25G
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Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers
Low C, et al.
Biophysical Journal, 95(9), 4315-4323 (2008)
Fei Ye et al.
eLife, 7 (2018-12-12)
INAD assembles key enzymes of the Drosophila compound eye photo-transduction pathway into a supramolecular complex, supporting efficient and fast light signaling. However, the molecular mechanism that governs the interaction between INAD and NORPA (phospholipase Cβ, PLCβ), a key step for
Qing Lu et al.
Molecular biology of the cell, 22(22), 4268-4278 (2011-10-04)
Myosin X (MyoX) is an unconventional myosin that is known to induce the formation and elongation of filopodia in many cell types. MyoX-induced filopodial induction requires the three PH domains in its tail region, although with unknown underlying molecular mechanisms.
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D
Freye-MC, et al.
Biochemistry, 42(3), 620-630 (2003)
Measurement of phosphoinositides in the zebrafish Danio rerio
Jones DR, et al.
Nature Protocols, 8(6), 1058-1058 (2013)

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