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H2270

Sigma-Aldrich

Hydrocortisone 21-hemisuccinate sodium salt

powder, BioReagent, suitable for cell culture

Synonym(s):
11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium salt, Cortisol 21-hemisuccinate sodium salt
Empirical Formula (Hill Notation):
C25H33NaO8
CAS Number:
Molecular Weight:
484.51
EC Number:
MDL number:
PubChem Substance ID:

biological source

synthetic (organic)

Quality Level

product line

BioReagent

Assay

≥90% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]

InChI

1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

InChI key

HHZQLQREDATOBM-CODXZCKSSA-M

Gene Information

human ... NR3C1(2908)

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1 of 4

This Item
H4881H0888H0135
Hydrocortisone BioReagent, suitable for cell culture

Sigma-Aldrich

H0888

Hydrocortisone

Hydrocortisone γ-irradiated, powder, BioXtra, suitable for cell culture

Sigma-Aldrich

H0135

Hydrocortisone

product line

BioReagent

product line

-

product line

BioReagent

product line

BioXtra

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥98%

assay

≥80% (HPLC)

form

powder

form

powder

form

powder

form

powder

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to very faintly yellow

solubility

ethanol: 1 mg/mL, clear

General description

Hydrocortisone for use in epithelial and endothelial adherent cell culture applications.

Application

Hydrocortisone 21-hemisuccinate sodium salt has been used as a supplement in Dulbecco′s modified Eagle medium/nutrient mixture F-12 (DMEM F12) for culturing oral squamous cell carcinoma (OSCC) cell lines and immortalized cone photoreceptor cell line.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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