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SAB4301607

Sigma-Aldrich

Anti-CD63

affinity isolated antibody

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Synonym(s):
LAMP-3, ME491, MLA1, OMA81H, TSPAN30
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:25-1:100
western blot: 1:500-1:2000

accession no.

NP_001244318

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CD63(967)

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SAB4301607

Anti-CD63

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

mouse

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

Gene Information

human ... CD63(967)

Gene Information

human ... CD63(967)

Gene Information

human ... CD63(967)

Gene Information

human ... CD63(967)

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General description

Cluster of differentiation (CD63) belongs to the tetraspanin family, with four transmembrane domains. It is localised in late endosomes and lysosomes. The gene is located on human chromosome 12q13.2. CD63 is a membrane bound glycoprotein.

Immunogen

Synthetic peptide of human CD63 molecule

Biochem/physiol Actions

Cluster of differentiation (CD63) acts as a platelet activation marker. It plays an important role in regulating cell proliferation, adhesion, motility and differentiation. CD63 acts as a prognostic marker for lung adenocarcinoma. Deficiency of CD63 is associated with Hermansky−Pudlak syndrome (HPS).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function
Wei ML
Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 19(1), 19-42 (2006)
Trafficking and function of the tetraspanin CD63
Pols MS and Klumperman J
Experimental Cell Research, 315(9), 1584-1592 (2009)
Dongdong Tian et al.
International journal of molecular medicine, 50(1) (2022-05-28)
Chronic obstructive pulmonary disease (COPD) is one of the major causes of death worldwide today, and its related morbidity has been predicted to show an increase in subsequent years. Recent studies have shown that Danshen, a Chinese herbal medicine, is
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes
De Leeuw RJ, et al.
Human Molecular Genetics, 13(17), 1827-1837 (2004)
Course of platelet activation markers after ischemic stroke
Marquardt L, et al.
Stroke, 33(11), 2570-2574 (2002)

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