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T2397

Sigma-Aldrich

Tyrode′s Salts

With sodium bicarbonate, liquid, sterile-filtered, suitable for cell culture

Synonym(s):

Tyrode′s buffer

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.75

sterility

sterile-filtered

Quality Level

form

liquid

quality

With sodium bicarbonate

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

components

glucose: 1.0 g/L (Dextro

Dextro)
NaHCO3: 1.0 g/L

shipped in

ambient

General description

Tyrode′s Salts solution is designed to work with mammalian cells. This balanced salt solution can be used for diluting protein components of media of natural origin. Balanced Salt solution plays a role in providing a buffer system to maintain the medium in optimum pH range (7.2-7.6), irrigating and diluting while maintaining the intra- and extracellular osmotic balance. It facilitates the maintenance of normal cell metabolism by giving water and bulk inorganic ions. Balanced Salt solution provides the energy source for cell metabolism by supplying nutrients.

Application

Tyrode′s Salts has been used:
  • to incubate sperms collected from cauda epididymis of rat, mouse, guinea pig, golden hamster and rabbit
  • for the transportation of lower uterine segment (LUS) strips from women
  • for the transportation of Cor.4U human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Ivan Kopljar et al.
Journal of pharmacological and toxicological methods, 91, 80-86 (2018-02-09)
Calcium-based screening of hiPS-CMs is a useful preclinical safety evaluation platform with the ability to generate robust signals that facilitates high-throughput screening and data analysis. However, due to the potential inherent toxicities, it is important to understand potential effects of
Gregor Seliger et al.
European journal of obstetrics, gynecology, and reproductive biology, 225, 172-180 (2018-05-08)
The purpose of this study was to assess, if the biomechanical properties of the lower uterine segment (LUS) in women with a previous cesarean section (CS) can be determined by ultrasound (US) elastography. The first aim was to establish an
Penghua Yang et al.
Nature communications, 10(1), 282-282 (2019-01-19)
Failure of neural tube closure results in severe birth defects and can be induced by high glucose levels resulting from maternal diabetes. MARCKS is required for neural tube closure, but the regulation and of its biological activity and function have
Wenlong Zhao et al.
Journal of cellular and molecular medicine, 22(3), 1755-1768 (2017-11-24)
Outer dense fibers (ODFs), as unique accessory structures in mammalian sperm, are considered to play a role in the protection of the sperm tail against shear forces. However, the role and relevant mechanisms of ODFs in modulating sperm motility and
Zheng-Zheng Li et al.
Bioscience reports, 40(1) (2020-01-07)
Cilia and flagella are critical organelles with conserved internal structures and diverse developmental and physiological processes according to cell type. Although the core components of structures are shared with thousands of associated proteins involved in cilia or flagella formation, we

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