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A6661

Sigma-Aldrich

Albumin, dinitrophenyl

lyophilized powder

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Synonym(s):
DNP-albumin human
CAS Number:
MDL number:
NACRES:
NA.25

biological source

human

form

lyophilized powder

extent of labeling

30-40 mol DNP per mol albumin

UniProt accession no.

storage temp.

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

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This Item
A1900SRP6516MSST0011
vibrant-m

A6661

Albumin, dinitrophenyl

vibrant-m

A1900

Albumin, Monomer bovine

vibrant-m

SRP6516

Albumin from human plasma

vibrant-m

MSST0011

SILuProt ALB Albumin human

biological source

human

biological source

bovine

biological source

human

biological source

human

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

form

lyophilized powder

form

lyophilized powder

form

lyophilized

form

lyophilized powder

Gene Information

human ... ALB(213)

Gene Information

bovine ... ALB(280717)

Gene Information

human ... ALB(213)

Gene Information

human ... ALB(213)

extent of labeling

30-40 mol DNP per mol albumin

extent of labeling

-

extent of labeling

-

extent of labeling

-

Application

Albumin, dinitrophenyl has been used to assess degranulation from rat mast cells by treatment of:
  • bakkenolide B
  • 4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1)
  • mifepristone
Used for detection in immunological analyses. Can be used as an immunological challenge to activate basophils via the IgE receptor.

Analysis Note

Source material has tested negative for HIV and HBsAg

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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B Jabril-Cuenod et al.
The Journal of biological chemistry, 271(27), 16268-16272 (1996-07-05)
Antigen receptors on T- and B-cells activate Ras through a signaling pathway that results in the tyrosine phosphorylation of Shc and the formation of a complex of Shc with the Grb2 adaptor protein. The high affinity receptor for immunoglobulin E
Xuan Che et al.
International journal of medical sciences, 17(2), 224-233 (2020-02-11)
Background: Adenomyosis is a quite common gynecological disorder and above 30% of patients have typical secondary and progressive dysmenorrhea. Current treatments still have many disadvantages and thereby the novel treatment aiming to relieve dysmenorrhea still needs to be further investigated.
Little, S.R. and Eisen, H.N.
Methods Immunol. Immunochem., 1, 128-128 (1967)
Carolin N Zorn et al.
Scientific reports, 8(1), 15467-15467 (2018-10-21)
Antigen (Ag)-mediated crosslinking of IgE-loaded high-affinity receptors for IgE (FcεRI) on mast cells (MCs) triggers activation of proinflammatory effector functions relevant for IgE-associated allergic disorders. The cytosolic tyrosine kinase BTK and the SH2-containing inositol-5'-phosphatase SHIP1 are central positive and negative
G J Heywood et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 51(4), 176-181 (2002-06-13)
Nicorandil is a potassium channel opener and nitric oxide (NO) donor, and the hypothesis was tested that these modes of action may inhibit cellular degranulation and release of tumour necrosis factor-alpha (TNF-alpha). TNF-alpha and beta-hexosaminidase secretion were measured from rat

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