T5251

D-(+)-Trehalose dihydrate

≥98.5% (HPLC), from Saccharomyces cerevisiae

• Synonym(s): α,α-Trehalose dihydrate, D-Trehalose dihydrate, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
• Empirical Formula (Hill Notation): C₁₂H₂₂O₁₁ · 2H₂O
• CAS Number: 6138-23-4
• Molecular Weight: 378.33
• Beilstein/REAXYS Number: 5322018
• EC Number: 202-739-6
• MDL number: MFCD00071594
• UNSPSC Code: 12352201
• PubChem Substance ID: 57654674
• NACRES: NA.25

Properties

• biological source: Saccharomyces cerevisiae
• assay: ≥98.5% (HPLC)
• form: powder
• optical activity: [α]/D 174 to 182 °, c = 1.0% (w/v) in water
• technique(s): HPLC: suitable; cryopreservation: suitable
• mp: 97-99 °C
• application(s): agriculture; agriculture; cell analysis; genomic analysis; life science and biopharma
• SMILES string: [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
• InChI key: DPVHGFAJLZWDOC-PVXXTIHASA-N

Description

General description

D-(+)-Trehalose, a disaccharide, acts as a chemical chaperone and serves as a carbohydrate reserve in microorganisms. It functions as an osmolyte, safeguarding cells against various environmental stresses. Further, it also plays a crucial role in protein stabilization during freeze drying, making it a valuable asset in the areas of biochemical, cell culture, and excipient research

Application

• Use as a cryoprotectant in a variety of cell freezing media
• Used in excipeint research

Biochem/physiol Actions

Trehalose is a non-reducing sugar formed from two glucose units joined by a 1-1 alpha bond. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.

Features and Benefits

• Prepared from Saccharomyces cerevisiae
• Suitable for use with HPLC and GC-MS(4)

Preparation Note

Prepared by the modified procedure of Payen, R., Can. J. Res., 27B, 749 (1949).

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)