671274

(R,R)-(-)-N,N'-ジメチル-1,2-シクロヘキサンジアミン

≥97.0% (GC)

• 別名: (R,R)-(−)-N,N′-Dimethyl-1,2-diaminocyclohexane
• 実験式（ヒル表記法）: C₈H₁₈N₂
• CAS番号: 68737-65-5
• 分子量: 142.24
• MDL番号: MFCD00671527
• UNSPSCコード: 12352116
• PubChem Substance ID: 24885095
• NACRES: NA.22
• アッセイ: ≥97.0% (GC)

特性

• アッセイ: ≥97.0% (GC)
• 光学活性: [α]/D -145±5°, c = 4.47 in chloroform
• mp: 39-44 °C
• 官能基: amine
• 保管温度: 2-8°C
• SMILES記法: CN[C@@H]1CCCC[C@H]1NC
• InChI: 1S/C8H18N2/c1-9-7-5-3-4-6-8(7)10-2/h7-10H,3-6H2,1-2H3/t7-,8-/m1/s1
• InChI Key: JRHPOFJADXHYBR-HTQZYQBOSA-N

詳細

詳細

(R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine is a N,N′-dimethylated derivative of enantiopure 1,2-diaminocyclohexane. It can be formed during the hydrolysis of (R_3a,R_7a)-1,3-(dimethyl)-2-phenyl-2,3,3a,4,5,6,7,7a-octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide using HCl-methanol.

アプリケーション

(R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine can be used:

• As a ligand in the preparation of 4H-benzo[f]imidazo[1,4]diazepin-6-one through multi-component Ullmann coupling reaction.
• In one of the key synthetic steps for the preparation of tricyclic γ-secretase modulators.
• To prepare chiral fluorous diamino-diol proligand, which is used in the synthesis of zirconium metal complexes applicable as catalysts in 1-hexene polymerization.

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H314
• 注意書き: P270 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): 165.2 °F - closed cup
• 引火点(℃): 74 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter