W297607

キニーネ 一塩酸塩 二水和物

≥95%, FG

• 別名: キニン 一塩酸塩 二水和物, キニン 塩酸塩 二水和物
• 実験式（ヒル表記法）: C₂₀H₂₄N₂O₂ · HCl · 2H₂O
• CAS番号: 6119-47-7
• 分子量: 396.91
• FEMA番号: 2976
• Beilstein: 6112655
• EC Number: 205-001-1
• 欧州評議会番号: 715
• MDL番号: MFCD00151248
• UNSPSCコード: 12164502
• PubChem Substance ID: 24901428
• Flavis 番号: 14.155
• NACRES: NA.21
• 官能: odorless
• グレード: FG; Halal; Kosher
• 由来生物: synthetic
• 食物アレルゲン: no known allergens

特性

• 由来生物: synthetic
• 品質水準: 400
• グレード: FG; Halal; Kosher
• 法規制遵守: EU Regulation 1334/2008 & 872/2012
• アッセイ: ≥95%
• 光学活性: [α]22/D −235°, c = 2 in 0.1 M HCl
• mp: 115-116 °C (dec.) (lit.)
• アプリケーション: flavors and fragrances
• 文書: see Safety & Documentation for available documents
• 食物アレルゲン: no known allergens
• 官能: odorless
• SMILES記法: Cl[H].[H]O[H].[H]O[H].[H][C@@]12CCN(C[C@@H]1C=C)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OC)cc34
• InChI: 1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1
• InChI Key: MPQKYZPYCSTMEI-FLZPLBAKSA-N

詳細

アプリケーション

• Rats can predict aversiveness of Active Pharmaceutical Ingredients.: This study explores the use of rats to predict the aversiveness of various active pharmaceutical ingredients (APIs), including Quinine hydrochloride dihydrate, by measuring behavioral responses. The findings suggest that animal models can be effective in preclinical assessments of API aversiveness, which is crucial for drug formulation and patient compliance (Soto et al., 2018).


• Impact of sodium lauryl sulfate in oral liquids on e-tongue measurements.: This research investigates the influence of sodium lauryl sulfate on electronic tongue measurements of bitterness in oral liquid formulations containing Quinine hydrochloride dihydrate. The study highlights the importance of excipients in modifying taste perception, which is significant for developing palatable pharmaceutical products (Immohr et al., 2016).

安全性情報

• ピクトグラム: GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H317,H334
• 注意書き: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• 危険有害性の分類: Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves