700095P

sitosterol

Avanti Research^™ - A Croda Brand

• 別名: stigmast-5-en-3β-ol; β-sitosterin
• 実験式（ヒル表記法）: C₂₉H₅₀O
• CAS番号: 83-46-5
• 分子量: 414.71
• MDL番号: MFCD00003631
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 詳細: 22,23-dihydrostigmasterol
• アッセイ: >99% (contains ~2% of the 24 alpha isomer, TLC)
• フォーム: powder
• 包装: pkg of 1 × 25 mg (700095P-25mg); pkg of 1 × 5 mg (700095P-5mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CC[C@H](C(C)C)CC)C)(CC3)C)CC=C2C1)C
• InChI: 1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
• InChI Key: KZJWDPNRJALLNS-VJSFXXLFSA-N

詳細

詳細

Sitosterol, also called as β-sitosterol, is synthesized through the mevalonate and deoxy xylulose pathways. Synthetically, it is synthesized from stigmasterol by Δ22–23 alkene group hydrogenation. Structurally sitosterol differ from cholesterol with ethyl (sitosterol) group in C24 position of side chain(65). Sitosterol is a lipid component of membranes. It corresponds to a molecular mass of 414.71 g/mol).

ß-sitosterol is a phytosterol (plant sterol) found in a wide variety of plants, including pecans, saw palmetto, avocados, pumpkin seed, rice bran, wheat germ, and soybeans. Chemically resembling cholesterol, phytosterols inhibit the absorption of cholesterol. Phytosterols have also been shown to have anticancer properties

アプリケーション

Sitosterol has been used as a sterol compound to test its interaction with human Mincle protein. It has also been used as a component of erythrocyte lipid model membrane for biophysical studies.

生物化学的／生理学的作用

Sitosterol promotes the antioxidant levels and is used as an effective anti-inflammatory, antiapoptotic and anticancer agent in medicinal preparations. It acts as a neutralizing agent for the venom from viper and cobra. Sitosterol acts on protein kinase C (PKC) and in the sphingomyelin cycle to mediate tumor progression inhibition.

包装

5 mL Amber Glass Screw Cap Vial (700095P-25mg)

5 mL Amber Glass Screw Cap Vial (700095P-5mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable