850520P

n-dodecyl-β-D-maltoside (DDM)

Avanti Research^™ - A Croda Brand

• 別名: DDM; lauryl maltoside; dodecyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside
• 実験式（ヒル表記法）: C₂₄H₄₆O₁₁
• CAS番号: 69227-93-6
• 分子量: 510.62
• MDL番号: MFCD00043012
• UNSPSCコード: 12161902
• NACRES: NA.25

特性

• 詳細: n-dodecyl-β-D-maltopyranoside
• アッセイ: >99% (contains <2% alpha isomer, TLC)
• フォーム: powder
• 分子量: 510.62 g/mol
• 包装: pkg of 1 × 1 g (850520P-1g); pkg of 1 × 25 g (850520P-25g); pkg of 1 × 5 g (850520P-5g)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: OC[C@H]1O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2
• InChI: 1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1
• InChI Key: NLEBIOOXCVAHBD-QKMCSOCLSA-N

詳細

詳細

n-dodecyl-β-D-maltoside (DDM) is a sugar-based surfactant.

DDM is the most widely used detergent for the isolation and purification of GPCR′s. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form.

アプリケーション

n-dodecyl-β-D-maltoside (DDM) has been used to solubilize mitochondrial extracts of fibroblasts to perform one-dimensional blue-native PAGE (BN-PAGE) analysis for assembled oxidative phosphorylation (OXPHOS) complexes.

生物化学的／生理学的作用

n-dodecyl-β-D-maltoside (DDM) exhibits biocompatibility and biodegradability. It serves as a facilitator of electron transfer in order to decrease the oxidation potential of 3,4-ethylenedioxythiophene (EDOT). It can also increase the solubility of EDOT in aqueous solution.

包装

125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850520P-25g)

20 mL Clear Glass Screw Cap Vial (850520P-1g)

30 mL Amber Wide Mouth Screw Cap Glass Bottle (850520P-5g)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable