M-132

N-メチル-N-(トリメチルシリル)トリフルオロアセトアミド

ampule of 10 × 1.2 mL, analytical standard, Cerilliant^®

• 別名: N-トリメチルシリル-N-メチルトリフルオロアセトアミド, MSTFA
• 化学式: CF₃CON(CH₃)Si(CH₃)₃
• CAS番号: 24589-78-4
• 分子量: 199.25
• Beilstein: 1941550
• EC Number: 246-331-6
• MDL番号: MFCD00000411
• UNSPSCコード: 41116107
• PubChem Substance ID: 329817869
• NACRES: NA.24

特性

• グレード: analytical standard
• 品質水準: 100
• 蒸気密度: >1 (vs air)
• 蒸気圧: 8.8 mmHg ( 27 °C)
• 反応適合性: reagent type: derivatization reagent; reaction type: Acylations
• 包装: ampule of 10 × 1.2 mL
• メーカー／製品名: Cerilliant^®
• テクニック: gas chromatography (GC): suitable
• 屈折率: n20/D 1.38 (lit.)
• bp: 130-132 °C (lit.)
• 密度: 1.075 g/mL at 25 °C (lit.)
• アプリケーション: forensics and toxicology
• フォーマット: neat
• 保管温度: −20°C
• SMILES記法: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
• InChI Key: MSPCIZMDDUQPGJ-UHFFFAOYSA-N

詳細

詳細

MSTFA (N-Methyl-N-trimethylsilylfluoroacetamide) is an important trimethylsilyl reagent, and a commonly applied reagent since it is highly reactive towards a broad range of compound classes. GC-MS optimization studies reveal the use of this reagent either alone or in combination with 1% of trimethylchlorosilane as a catalyst for silylation of complex mixtures. It has similar reactivity as BSA and BSTFA.

アプリケーション

MSTFA reagent may be used as a derivatizing agent in the following:

• Analysis of estrogen steroids such as estrone (E1), 17α-ethinylestradiol (EE2), and trenbolone acetate metabolites, melengestrol in environmental matrices using gas chromatography coupled to mass spectrometry (GC-MS).
• Quantification of ibuprofen, naproxen, ketoprofen, and diclofenac in wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).

特徴および利点

• Very volatile of TMS-acetamides.
• More volatile than BSA or BSTFA but with similar silylation strength.
• Useful in the analysis of volatile trace materials.
• Used in the preparation of volatile and thermally stable derivatives for GC and MS analysis.

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Warning
• 危険有害性情報: H226,H315,H319,H335
• 注意書き: P210 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 78.8 °F - closed cup
• 引火点(℃): 26 °C - closed cup