341482

Ferritin, Human Liver

Ferritin, Human Liver, CAS 9007-73-2, is a native, sterile-filtered ferritin that is suitable for use in immunoassays, as an immunogen, and in enzyme/radiolabeling.

• 別名: Ferritin, Human Liver
• CAS番号: 9007-73-2
• MDL番号: MFCD00081593
• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• 由来生物: human
• 品質水準: 100
• アッセイ: ≥95% (SDS-PAGE)
• 形状: liquid
• メーカー／製品名: Calbiochem^®
• 保管条件: do not freeze
• テクニック: enzyme immunoassay: suitable
• 不純物: Antibodies to HIV1, HIV2, Hepatitis B, Hepatitis C, tested negative (by certified tests)
• 溶解性: water: soluble
• 適合性: suitable for immunoassay
• タンパク質IDアクセッション番号: AAA35832.1
• UniProtアクセッション番号: P02792; P02794
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 遺伝子情報: human ... FTH1(2495) , FTL(2512)

詳細

詳細

Research area: Cell signaling

Ferritin is a major iron storage protein. It exists in a two functionally and genetically different subunits namely, the acidic, heavy or H-chain and the basic, light or L-chain. Native ferritin from human liver. Sterile-filtered.

アプリケーション

Ferritin is suitable for use in immunofluorescence assay, immunoassays, as an immunogen, and in enzyme/radiolabeling.

生物化学的／生理学的作用

Ferritin is a crucial protein that has multiple functions in iron metabolism and immune regulation. It helps in maintaining the iron balance. H-ferritin is involved in various processes such as regulating immune function, hematopoiesis, hepatocyte apoptosis, and cell differentiation. Additionally, ferritin can act as a proinflammatory cytokine through protein kinase C-zeta (PKC-ζ) and nuclear factor kappa B (NFκB) signaling pathways in certain cells.(1) Ferritin serves as both an immune-suppressor and a signaling molecule, contributing to the regulation of lymphoid and myeloid cell proliferation.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

物理的形状

In 0.9% NaCl, 0.1% NaN₃, pH 7.0.

その他情報

Addison, J.M., et al. 1983. FEBS Lett.164, 139.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable