495455

Oligomycin

≥90% (mixture of A, B, and C isomers, HPLC), powder, Antibiotic, Calbiochem

• 別名: Oligomycin
• 実験式（ヒル表記法）: C₄₅H₇₄O₁₁
• CAS番号: 1404-19-9
• 分子量: 791.06
• MDL番号: MFCD01779388
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 製品名: Oligomycin, A mixture of A, B, and C isomers.
• 品質水準: 100
• アッセイ: ≥90% (mixture of A, B, and C isomers, HPLC)
• フォーム: powder
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 輸送温度: ambient
• 保管温度: −20°C
• InChI: 1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+
• InChI Key: MNULEGDCPYONBU-ZUSSGZTJSA-N

詳細

詳細

A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Membrane-bound mitochondrial ATPase (F1)

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

再構成

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.

その他情報

Wolvetang, E.J., et al. 1994. FEBS Lett.339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable