538927

15d-PGJ₂

A metabolite of PGD₂that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells.

• 別名: 15d-PGJ₂, Prostaglandin J₂, 15-Deoxy-Δ ^12,14, PPAR Agonist VII, PPARγ Agonist VI
• 実験式（ヒル表記法）: C₂₀H₂₈O₃
• CAS番号: 87893-55-8
• 分子量: 316.43
• MDL番号: MFCD00065806
• UNSPSCコード: 12352211
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: oil
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 溶解性: DMSO: 25 mg/mL; ethanol: 25 mg/mL
• 輸送温度: wet ice
• 保管温度: −20°C
• InChI: 1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1
• InChI Key: VHRUMKCAEVRUBK-GODQJPCRSA-N

詳細

詳細

A metabolite of PGD₂ that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
A natural ligand for PPARγ-dependent adipogenesis

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Harmful (C)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell83, 813.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable