C7805

Anti-Collagen Type III (COL3A1) Antibody

mouse monoclonal, FH-7A

• 別名: Anti-Collagen III antibody
• MDL番号: MFCD00239753
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 製品名: モノクロナール抗コラーゲン, III型 マウス宿主抗体, clone FH-7A, ascites fluid
• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: ascites fluid
• 抗体製品タイプ: primary antibodies
• クローン: FH-7A, monoclonal
• 分子量: antigen 70 kDa
• 含みます: 15 mM sodium azide
• 交差性: human, rat
• テクニック: dot blot: suitable; immunohistochemistry (frozen sections): 1-4,000 using frozen sections of human skin; indirect ELISA: suitable; western blot: suitable using a denatured-reduced preparation
• アイソタイプ: IgG1
• UniProtアクセッション番号: P02461
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... COL3A1(1281) ; rat ... Col3a1(84032)

詳細

詳細

Collagen is a fibrous protein present in the extracellular framework of all vertebrates. Collagen type III is a 300 kD molecule that belongs to fibrillar collagens family found mainly in skin, blood vessels, liver, placenta, tongue and thymus. This collagen is directly or indirectly involved in several genetic diseases like Ehlers-Danlos type IV disease. Monoclonal anti-collagen type III antibody can be used to determine the interstitial collagen I and III content in total protein homogenates. It is also used to study the immunolocalization of collagen type III in normal and neoplastic tissue. Mouse monoclonal anti-collagen type III antibody reacts specifically with native and denatured collagen type III but not with collagen types I, II, IV, V, VI, and X.

Monoclonal Anti-Collagen Type III (mouse IgG1 isotype) is derived from the FH-7A hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human collagen type III.

特異性

Monoclonal Anti-Collagen Type III reacts specifically with native and denatured collagen type III. It does not recognize collagen types I, II, IV, V, VI, and X.

免疫原

ヒトIII型コラ-ゲン。

アプリケーション

Monoclonal Anti-Collagen, Type III antibody produced in mouse has also been used in enzyme linked immunosorbent assay (ELISA) and immunohistochemistry.

Monoclonal anti-collagen type III antibody has been used in immunofluorescence and western blot.

生物化学的／生理学的作用

This collagen is directly or indirectly involved in several genetic diseases like Ehlers-Danlos type IV disease. Monoclonal anti-collagen type III antibody can be used to determine the interstitial collagen I and III content in total protein homogenates.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable