D7321

Diosmetin

• 別名: 3′,5,7-Trihydroxy-4′-methoxyflavone, 4′-Methylluteolin, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, Luteolin 4′-methyl ether
• 実験式（ヒル表記法）: C₁₆H₁₂O₆
• CAS番号: 520-34-3
• 分子量: 300.26
• Beilstein: 294492
• EC Number: 208-291-8
• MDL番号: MFCD00017425
• UNSPSCコード: 12352205
• PubChem Substance ID: 329798848
• NACRES: NA.25

特性

• アッセイ: ≥98% (HPLC)
• 品質水準: 200
• フォーム: powder
• 色: light yellow to yellow
• 溶解性: DMSO: 1 mg/mL, clear, faintly yellow to greenish-yellow
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: 2-8°C
• SMILES記法: COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
• InChI Key: MBNGWHIJMBWFHU-UHFFFAOYSA-N

詳細

詳細

Diosmetin is a methylated aglycone flavone of diosmin. It is present abundantly in citrus fruits, Olea europaea L. (olive tree) leaves, and in the legume of Acacia farnesiana tree.

アプリケーション

Diosmetin has been used to test its protective effects on chronic stress memory and cognitive impairment in mice model.

生物化学的／生理学的作用

Diosmetin exhibits anti-inflammatory, anti-cancer, antimicrobial, phytoestrogenic, and neuroprotective properties. It displays cytoprotective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by inhibiting nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome and activating nuclear factor erythroid 2–related factor 2 (Nrf2).

Flavonoid from Citrus limon. Antioxidant. Inhibits carcinogen activation by inhibiting the CYP1A1 enzyme.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable