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Merck

F3512

Sigma-Aldrich

Anti-Human IgG (whole molecule)−FITC antibody produced in goat

IgG fraction of antiserum, buffered aqueous solution

別名:

Goat Anti-Human IgG (whole molecule)−Fluorescein isothiocyanate

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

goat

品質水準

結合体

FITC conjugate

抗体製品の状態

IgG fraction of antiserum

抗体製品タイプ

secondary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

保管条件

protect from light

テクニック

immunofluorescence: 1:32-1:64 using Hep2 cells

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

詳細

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders . Specificity of anti-human IgG (whole molecule)-FITC antibody for human IgG is determined by immunoelectrophoresis against purified human IgA, IgG, IgM, and Bence Jones κ and λ myeloma proteins.
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. The two heavy chains and two light chains of IgG are connected by a disulfide bond. It is a glycoprotein and mainly helps in immune defense. IgG is usually found as a monomer. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. About 70 percent of the total immunoglobulin consists of IgG. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

免疫原

Pooled normal human serum

アプリケーション

Anti-Human IgG (whole molecule)-FITC antibody has been used:
  • in nucleolar staining
  • in single color fluorescent labeling for the detection of lytically induced cells
  • to detect the model antigen
  • in immunohistochemistry
  • in immunofluorescence

Anti-Human IgG (whole molecule)-FITC antibody may be used for anti-nuclear antibody (ANA) assays. The antibody may also be used in FACS-based assays.

物理的形状

0.01 M PBS溶液(pH 7.4, 15 mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

F3512-2ML:
F3512-VAR:
F3512-.5ML:
F3512-BULK:
F3512-1ML:


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試験成績書(COA)

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文書ライブラリにアクセスする

J Cheng et al.
Molecular and cellular biology, 21(18), 6198-6209 (2001-08-18)
Sphingolipids are major components of the plasma membrane of eukaryotic cells and were once thought of merely as structural components of the membrane. We have investigated effects of inhibiting sphingolipid biosynthesis, both in germinating spores and growing hyphae of Aspergillus
A model system for concurrent detection of antigen and antibody based on immunological fluorescent method
Cao Y C
Journal of Spectroscopy (New York, NY, United States), 2015 (2015)
Ontogeny and distribution of Fc gamma receptors in the human placenta. Transport or immune surveillance?
Bright N A, et al.
Journal of Anatomy, 184(Pt 2), 297-297 (1994)
Rhiannon S McBean et al.
Transfusion, 55(6 Pt 2), 1451-1456 (2014-12-20)
Until recently, SARAH (SARA) was a low-frequency antigen within the 700 series (700.052). SARA was discovered in Australia and subsequently described in Canada where anti-SARA was implicated in severe hemolytic disease of the fetus and newborn (HDFN). This study investigated
A E Till et al.
The British journal of dermatology, 142(5), 885-892 (2000-05-16)
The cutaneous microbiology and antibody status to Propionibacterium acnes of patients with persistent (males, n = 32; females, n = 33) and late-onset (females, n = 25) acne were compared with individuals with adolescent acne (males, n = 22; females

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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