おすすめの製品
製品名
線維芽細胞成長因子-塩基性, FGF-Basic, from human, recombinant, expressed in E. coli, carrier free
由来生物
human
品質水準
リコンビナント
expressed in E. coli
アッセイ
≥97% (SDS-PAGE)
フォーム
lyophilized powder
有効性
<1 ng/mL Biological Activity EC50
分子量
16.0 kDa
包装
pkg of 4X25 μg
pkg of 25 μg
保管条件
avoid repeated freeze/thaw cycles
色
white to faint yellow cast
溶解性
water: soluble 0.025 mg, clear, colorless to faintly yellow
UniProtアクセッション番号
保管温度
−20°C
遺伝子情報
human ... FGF2(2247)
詳細
bFGFは、多様な臓器で発見され、幅広い細胞型で作用し、多機能的作用を有するため、ヘパリン結合増殖因子(クラスIIまたはβ)、眼由来増殖因子I、軟骨由来増殖因子、アストログリア増殖因子II5など、多数の同義語が認められます。精製ウシおよびヒトbFGF は、3個の連続したアミノ酸が異なっており3、生物学的および免疫学的に交差反応します。
引用
1. Gospodarowicz, D., Localization of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Nature, 249, 123-127 (1974).
2. Gospodarowicz, D. et al., Structural characterization and biological functions of fibroblast growth factor. Endo. Rev., 8, 95-114 (1987).
3. Esch, F. et al., Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82, 6507-6511 (1985).
4. Neufeld, G., and Gospodarowicz, D., Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J. Biol. Chem., 261, 5631-5637 (1986).
5. Lobb, R.R. et al., Purification of heparin-binding growth factors. Anal. Biochem., 154, 1-14 (1986).
6. Abraham, J.A., Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5, 2523- 2528 (1986).
2. Gospodarowicz, D. et al., Structural characterization and biological functions of fibroblast growth factor. Endo. Rev., 8, 95-114 (1987).
3. Esch, F. et al., Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82, 6507-6511 (1985).
4. Neufeld, G., and Gospodarowicz, D., Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J. Biol. Chem., 261, 5631-5637 (1986).
5. Lobb, R.R. et al., Purification of heparin-binding growth factors. Anal. Biochem., 154, 1-14 (1986).
6. Abraham, J.A., Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5, 2523- 2528 (1986).
保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
F3685-25UG-PW:
F3685-25UG:
F3685-BULK:
F3685-VAR:
F3685-4X25UG:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
この製品を見ている人はこちらもチェック
Aimee Cheesbrough et al.
Advanced materials (Deerfield Beach, Fla.), 34(18), e2110441-e2110441 (2022-03-02)
Generating skeletal muscle tissue that mimics the cellular alignment, maturation, and function of native skeletal muscle is an ongoing challenge in disease modeling and regenerative therapies. Skeletal muscle cultures require extracellular guidance and mechanical support to stabilize contractile myofibers. Existing
Parash Parajuli et al.
Developmental cell, 45(6), 712-725 (2018-06-20)
Cancer cachexia is characterized by extreme skeletal muscle loss that results in high morbidity and mortality. The incidence of cachexia varies among tumor types, being lowest in sarcomas, whereas 90% of pancreatic ductal adenocarcinoma (PDAC) patients experience severe weight loss.
Marta E Capala et al.
Cancers, 15(2) (2023-01-22)
Head and neck squamous cell carcinoma (HNSCC) displays a large heterogeneity in treatment response, and consequently in patient prognosis. Despite extensive efforts, no clinically validated model is available to predict tumor response. Here we describe a functional test for predicting
Xiaotang Wang et al.
MedComm, 4(1), e198-e198 (2022-12-31)
Stem cell therapy is a promising strategy to rescue visual impairment caused by retinal degeneration. Previous studies have proposed controversial theories about whether in situ retinal stem cells (RSCs) are present in adult human eye tissue. Single-cell RNA sequencing (scRNA-seq)
Heli Honkala et al.
PathoGenetics, 2(1), 2-2 (2009-04-30)
Hydrolethalus syndrome (HLS) is a severe fetal malformation syndrome characterized by multiple developmental anomalies, including central nervous system (CNS) malformation such as hydrocephaly and absent midline structures of the brain, micrognathia, defective lobation of the lungs and polydactyly. Microscopically, immature
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）