SAB4200602

Anti-Actin (α-Sarcomeric) antibody, Mouse monoclonal

~1.0 mg/mL, clone 5C5, purified from hybridoma cell culture

• 別名: Anti-AA959943, Anti-ACTA1, Anti-ALPHA SKELETAL ACTIN, Anti-ALPHA1 ACTIN, Anti-ASMA, Anti-Acta-2, Anti-Acts, Anti-Actsk-1, Anti-CFTD, Anti-CFTDM, Anti-Fetal isoform of skeletal alpha-actin, G-actin, Anti-MPFD, Anti-NEM1, Anti-RP5-1068B5.2, Anti-actin, alpha 1, skeletal muscle
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: 5C5, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~42 kDa
• 化学種の反応性: human, carp, bovine, frog, sheep, rabbit, rat, snake, guinea pig
• 濃度: ~1.0 mg/mL
• テクニック: immunoblotting: suitable; immunohistochemistry: 1-2 μg/mL using formalin-fixed, paraffin embedded human tongue; indirect ELISA: suitable
• アイソタイプ: IgM
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ACTA1(58)

詳細

詳細

Monoclonal Anti-Actin (α-Sarcomeric) (mouse IgM isotype) is derived from the hybridoma 5C5 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified rabbit striated muscle. Actin is one of the major cytoskeletal proteins in eukaryotic cells.

免疫原

purified rabbit striated muscle

アプリケーション

Monoclonal Anti-Actin (α-Sarcomeric) antibody produced in mouse has been used in:

• western blotting
• enzyme linked immunosorbent assay (ELISA)
• immunohistochemistry

生物化学的／生理学的作用

Actin plays an essential role in various cellular processes including cell migration, cytokinesis, vesicle transport, and contractile force generation. Pathological conditions influenced by genetic and/or environmental factors causes variations in the sarcomeric actin filaments. These variations in the actin filaments leads to the development of congenital myopathy, a genetic muscle disorder.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable